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Rotational behaviour of red blood cells in suspension: a mesoscale simulation study.
MedLine Citation:
PMID:  21536581     Owner:  NLM     Status:  In-Data-Review    
Abstract/OtherAbstract:
The nature of blood as a suspension of red blood cells makes computational haemodynamics a demanding task. Our coarse-grained blood model, which builds on a lattice Boltzmann method for soft particle suspensions, enables the study of the collective behaviour of the order of 10(6) cells in suspension. After demonstrating the viscosity measurement in Kolmogorov flow, we focus on the statistical analysis of the cell orientation and rotation in Couette flow. We quantify the average inclination with respect to the flow and the nematic order as a function of shear rate and haematocrit. We further record the distribution of rotation periods around the vorticity direction and find a pronounced peak in the vicinity of the theoretical value for free model cells, even though cell-cell interactions manifest themselves in a substantial width of the distribution.
Authors:
F Janoschek; F Mancini; J Harting; F Toschi
Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Philosophical transactions. Series A, Mathematical, physical, and engineering sciences     Volume:  369     ISSN:  1364-503X     ISO Abbreviation:  Philos Transact A Math Phys Eng Sci     Publication Date:  2011 Jun 
Date Detail:
Created Date:  2011-05-03     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  101133385     Medline TA:  Philos Transact A Math Phys Eng Sci     Country:  England    
Other Details:
Languages:  eng     Pagination:  2337-44     Citation Subset:  IM    
Affiliation:
Department of Applied Physics, Eindhoven University of Technology, , PO Box 513, 5600 MB Eindhoven, The Netherlands.
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