| Rotational atherectomy multicenter registry: acute results, complications and 6-month angiographic follow-up in 709 patients. | |
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MedLine Citation:
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PMID: 8077533 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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OBJECTIVES: The purpose of this study was to describe data collected for an industry-sponsored multicenter registry of rotational atherectomy. BACKGROUND: Several new devices are in use or under development for coronary atherectomy. The clinical role for each is in part defined by descriptive registry data. METHODS: We describe results in 709 consecutive patients undergoing 743 procedures representing 874 lesions. The majority of lesions were in the left anterior descending coronary artery. Lesion morphology was described as eccentric (61.1%), calcified (32%), tortuous (26.6%) and long (24.9%), with previous intervention in 32.7%. RESULTS: Overall procedural success rate, including lesions treated with rotational atherectomy alone and with balloon angioplasty was 94.7% and did not vary between lesion type, location, characteristics or severity. Previously treated lesions had a significantly higher success rate (97.4%, p = 0.04) than new lesions. Major complications, including death 0.8% (95% confidence interval [CI] 0.3% to 1.7%), Q wave myocardial infarction 0.9% (95% CI 0.4% to 1.9%) and emergent coronary artery bypass surgery 1.7% (95% CI 0.9% to 3.0%), were similar to other reported devices and were associated with length and number of lesions treated. Non-Q wave myocardial infarction occurred in 3.8% of patients and was significantly associated with female gender and history of previous myocardial infarction. Abrupt occlusion occurred in 3.1% of patients and was significantly associated with bifurcated lesions and the use of adjunctive therapy. Angiographic evidence of dissection was seen in 10.5% (95% CI 8.3% to 12.7%) of patients and was significantly associated with more complex lesions, such as eccentric, long, calcified and American College of Cardiology/American Heart Association type C lesions. Overall restenosis rate was 37.7%, determined with 6-month angiography, representing 64% of treated lesions. Higher restenosis rates were associated only with poorer initial treatment outcome, diabetes and lower follow-up angiographic rate per reporting center. CONCLUSIONS: Rotational atherectomy appears to be a safe method of treatment with a high success rate in a broad spectrum of lesion types, with restenosis rates similar to other techniques. Further conclusions will require randomized trials. |
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Authors:
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D C Warth; M B Leon; W O'Neill; N Zacca; N L Polissar; M Buchbinder |
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Publication Detail:
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Type: Journal Article; Research Support, Non-U.S. Gov't |
Journal Detail:
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Title: Journal of the American College of Cardiology Volume: 24 ISSN: 0735-1097 ISO Abbreviation: J. Am. Coll. Cardiol. Publication Date: 1994 Sep |
Date Detail:
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Created Date: 1994-10-06 Completed Date: 1994-10-06 Revised Date: 2010-03-24 |
Medline Journal Info:
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Nlm Unique ID: 8301365 Medline TA: J Am Coll Cardiol Country: UNITED STATES |
Other Details:
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Languages: eng Pagination: 641-8 Citation Subset: AIM; IM |
Affiliation:
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Providence Medical Center, Heart Center, Seattle, Washington 98124-1008. |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Aged Analysis of Variance Angioplasty, Transluminal, Percutaneous Coronary Atherectomy, Coronary* / adverse effects, methods, mortality Coronary Artery Bypass Coronary Artery Disease / mortality, surgery*, therapy Coronary Vessels / injuries Female Humans Male Middle Aged Multivariate Analysis Myocardial Infarction / etiology Recurrence Registries Rotation Sex Factors |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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