| Rotablation in the drug eluting era: immediate and long-term results from a single center experience. | |
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MedLine Citation:
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PMID: 20459456 Owner: NLM Status: In-Process |
Abstract/OtherAbstract:
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The aim of this study was to investigate the immediate and long-term outcome of patients who were treated with rotational atherectomy (RA) to facilitate the delivery of drug eluting stents (DES) in heavily calcified lesions. We analyzed 150 consecutive patients who underwent RA and subsequently DES implantation in our institution. The patients had heavily calcified coronary artery lesions requiring plaque modification prior to conventional angioplasty and stent implantation. Rotational atherectomy was performed using the standard Boston Scientific Rotablator system. A 2-burr stepped approach was selected in most of the cases. Following successful modification of the plaque, the angioplasty was performed with a balloon at low pressure to avoid dissection and a DES was implanted. The mean follow up period was 3 years (max. 78 months). Follow-up data included all cause death, stroke, myocardial infarction (MI), recurrent angina, re-hospitalization, target lesion revascularization (TLR), target vessel revascularization (TVR), and long-term duration of dual antiplatelet therapy. The rate of recurrent angina and MI during follow up was low (3.3%) and the overall major adverse cardiac events (MACE) rate was 11.3%. No MACE occurred during hospitalization. There was no relationship between discontinuation of clopidogrel and occurrence of death or MI. The combined approach of RA-DES has a favorable effect when dealing with heavily calcified lesions in both the angiographic and clinical outcomes. No safety concerns are observed up to 6 years. |
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Authors:
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Nick Mezilis; Petros Dardas; Vlasis Ninios; Dimitrios Tsikaderis |
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Publication Detail:
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Type: Journal Article Date: 2010-04-28 |
Journal Detail:
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Title: Journal of interventional cardiology Volume: 23 ISSN: 1540-8183 ISO Abbreviation: J Interv Cardiol Publication Date: 2010 Jun |
Date Detail:
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Created Date: 2010-07-19 Completed Date: - Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 8907826 Medline TA: J Interv Cardiol Country: United States |
Other Details:
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Languages: eng Pagination: 249-53 Citation Subset: IM |
Affiliation:
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St. Luke's Hospital, Cardiology Department, Thessaloniki, Greece. mezilis@otenet.gr |
Export Citation:
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Descriptor/Qualifier:
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| Comments/Corrections | |
Comment In:
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J Interv Cardiol. 2010 Jun;23(3):254-5
[PMID:
20636845
]
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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