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Rosai-Dorfman syndrome affecting the lacrimal gland.
MedLine Citation:
PMID:  12045917     Owner:  NLM     Status:  Publisher    
Abstract/OtherAbstract:
This is a case report of Rosai-Dorfman syndrome in a 36-year-old Caucasian male, involving the lacrimal gland, cervical lymph nodes, nasal and sinusal mucosa. It was successfully treated with appropriate immunosuppression. He had initially presented to the ENT surgeon with nasal and sinusal mucosal thickening and bleeding. Cervical lymph node biopsy produced a histological diagnosis compatible with Rosai-Dorfman disease. Later he developed an acute red proptotic eye. He had severe proptosis due to an enlarged lacrimal gland. He refused surgical excision of the tumour, which is suggested if there is an ocular adnexal involvement. Conservative treatment with systemic steroid resulted in the resolution of lacrimal gland swelling, nasal sinusal mucosal thickening and cervical lymphadenopathy. Previous studies have shown that patients with Rosai-Dorfman syndrome are often black males1 and require surgery.
Authors:
Ashwin Reddy; Bijan Beigi; Evangelos Linardos
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Publication Detail:
Type:  JOURNAL ARTICLE    
Journal Detail:
Title:  Orbit (Amsterdam, Netherlands)     Volume:  20     ISSN:  1744-5108     ISO Abbreviation:  Orbit     Publication Date:  2001 Sep 
Date Detail:
Created Date:  2002-Jun-4     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  8301221     Medline TA:  Orbit     Country:  -    
Other Details:
Languages:  ENG     Pagination:  239-242     Citation Subset:  -    
Affiliation:
Department of Ophthalmology, Norfolk & Norwich University Hospital, Norwich, NR2 3TU, England, U.K. bijanbeigi@ukonline.co.uk
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