Document Detail


Rosai Dorfman disease--a rare entity report of two cases with nodal and extranodal involvement.
MedLine Citation:
PMID:  18988397     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Rosai Dorfman Disease (RDD) also known as Sinus Histiocytosis with Massive Lymphadenopathy (SHML)is a very rare variety of reactive histiocytoses. It commonly involves cervical lymph nodes; although involvement of other lymph node regions, skin and other organ involvement can occur. It has a good prognosis so there is a need to differentiate it from other lympho proliferative disorders of poorer prognosis. We present two cases of this rare disorder illustrating its clinical spectrum; a 22 years old woman with involvement of submandibular lymph nodes, nasal septum and sub-glottic region and a 45 years old male with prominent skin involvement.
Authors:
Jawad Jalil; Nasser Rashid Dar; Mobeen Shafique
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  JPMA. The Journal of the Pakistan Medical Association     Volume:  58     ISSN:  0030-9982     ISO Abbreviation:  J Pak Med Assoc     Publication Date:  2008 Jun 
Date Detail:
Created Date:  2008-11-07     Completed Date:  2008-12-05     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  7501162     Medline TA:  J Pak Med Assoc     Country:  Pakistan    
Other Details:
Languages:  eng     Pagination:  338-40     Citation Subset:  IM    
Affiliation:
Department of Paediatrics, Combined Military Hospital, Bahawalpur.
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MeSH Terms
Descriptor/Qualifier:
Adult
Cyclophosphamide / therapeutic use
Female
Histiocytes / pathology
Histiocytosis, Sinus / diagnosis*,  drug therapy,  physiopathology
Humans
Immunosuppressive Agents / therapeutic use
Male
Methotrexate / therapeutic use
Middle Aged
Young Adult
Chemical
Reg. No./Substance:
0/Immunosuppressive Agents; 50-18-0/Cyclophosphamide; 59-05-2/Methotrexate

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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