Document Detail

Rosacea fulminans triggered by high-dose vitamins B6 and B12.
MedLine Citation:
PMID:  11763399     Owner:  NLM     Status:  MEDLINE    
Rosacea fulminans is a rare variant of rosacea conglobata that occurs almost exclusively in women well past adolescence. The aetiology is unknown, although immunological, hormonal, and vascular factors have been suggested. We report the case of a 17-year-old girl with rosacea fulminans that was temporally associated with daily ingestion of high-dose vitamin B supplements. The onset was sudden and cosmetically disabling. The eruption improved when the vitamin supplement was discontinued and a therapeutic regimen including isotretinoin and methylprednisolone was introduced. It seems appropriate to consider the possibility of such a vitamin B-triggered condition in cases of subjects presenting new or exacerbating facial eruptions.
T Jansen; R Romiti; A Kreuter; P Altmeyer
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Publication Detail:
Type:  Case Reports; Journal Article    
Journal Detail:
Title:  Journal of the European Academy of Dermatology and Venereology : JEADV     Volume:  15     ISSN:  0926-9959     ISO Abbreviation:  J Eur Acad Dermatol Venereol     Publication Date:  2001 Sep 
Date Detail:
Created Date:  2001-12-12     Completed Date:  2002-02-28     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  9216037     Medline TA:  J Eur Acad Dermatol Venereol     Country:  Netherlands    
Other Details:
Languages:  eng     Pagination:  484-5     Citation Subset:  IM    
Department of Dermatology and Allergology, Ruhr-University Bochum, Germany.
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MeSH Terms
Dietary Supplements / adverse effects*
Dose-Response Relationship, Drug
Drug Eruptions / diagnosis,  etiology*
Facial Dermatoses / chemically induced,  diagnosis
Follow-Up Studies
Risk Assessment
Rosacea / chemically induced*,  diagnosis
Severity of Illness Index
Vitamin B 12 / administration & dosage,  adverse effects*
Vitamin B 6 / administration & dosage,  adverse effects*
Reg. No./Substance:
68-19-9/Vitamin B 12; 8059-24-3/Vitamin B 6

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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