Document Detail

Room air resuscitation versus oxygen resuscitation in the delivery room.
MedLine Citation:
PMID:  16292139     Owner:  NLM     Status:  MEDLINE    
The use of 100% oxygen for delivery room resuscitation is currently the recommended standard of the American Academy of Pediatrics and the Neonatal Resuscitation Program. However, there is mounting evidence from animal and human studies suggesting that resuscitation with room air (RA, 21% oxygen), including positive pressure ventilation with bag and face mask, may be as effective as that with 100% oxygen, and that the use of 100% oxygen may pose a risk of adverse physiologic sequelae. Resuscitation with RA has been demonstrated to result in faster recovery and improved neonatal mortality in comparison to 100% oxygen resuscitation. In addition, studies of normal oxygen saturation immediately after birth suggest delivery room personnel may be rushing to high saturation unnecessarily. The question for perinatal medical and nursing personnel involved in newborn resuscitation in the delivery room is whether the use of RA reduces the possible adverse effects of 100% oxygen, including delay in short-term stabilization, death, neurological disability, and possible secondary oxygen free radical injury. A systematic synopsis of both animal studies and human studies involving the advantages, disadvantages, possible risks, and short- and long-term effects of these 2 methods of resuscitation is presented.
Karen E Corff; Debra L McCann
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Publication Detail:
Type:  Journal Article; Review    
Journal Detail:
Title:  The Journal of perinatal & neonatal nursing     Volume:  19     ISSN:  0893-2190     ISO Abbreviation:  J Perinat Neonatal Nurs     Publication Date:    2005 Oct-Dec
Date Detail:
Created Date:  2005-11-18     Completed Date:  2006-02-16     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  8801387     Medline TA:  J Perinat Neonatal Nurs     Country:  United States    
Other Details:
Languages:  eng     Pagination:  379-90     Citation Subset:  N    
Children's Hospital, Department of Pediatrics, Section of Neonatology, University of Oklahoma Health Sciences Center, Oklahoma City, OK 73190, USA.
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MeSH Terms
Animals, Newborn
Asphyxia Neonatorum / therapy*
Infant, Newborn
Oxygen Inhalation Therapy / methods*
Positive-Pressure Respiration / methods*
Resuscitation / methods*

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