Document Detail


Room-temperature aromatization of tetrahydro-β-carbolines by 2-iodoxybenzoic acid: utility in a total synthesis of eudistomin U.
MedLine Citation:
PMID:  20715768     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
2-Iodoxybenzoic acid is a convenient reagent for the dehydrogenation of tetrahydro-β-carbolines to their aromatic forms under mild conditions. The utility of the method was demonstrated in a total synthesis of the marine indole alkaloid eudistomin U.
Authors:
Joseph D Panarese; Stephen P Waters
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Publication Detail:
Type:  Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  Organic letters     Volume:  12     ISSN:  1523-7052     ISO Abbreviation:  Org. Lett.     Publication Date:  2010 Sep 
Date Detail:
Created Date:  2010-09-10     Completed Date:  2010-12-21     Revised Date:  2013-05-29    
Medline Journal Info:
Nlm Unique ID:  100890393     Medline TA:  Org Lett     Country:  United States    
Other Details:
Languages:  eng     Pagination:  4086-9     Citation Subset:  IM    
Affiliation:
Department of Chemistry, The University of Vermont, 82 University Place, Burlington, Vermont 05405, USA.
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MeSH Terms
Descriptor/Qualifier:
Carbolines / chemical synthesis,  chemistry*
Iodobenzoates / chemistry*
Molecular Structure
Temperature
Grant Support
ID/Acronym/Agency:
P20 RR016462-07/RR/NCRR NIH HHS; P20 RR16462/RR/NCRR NIH HHS
Chemical
Reg. No./Substance:
0/Carbolines; 0/Iodobenzoates; 155885-64-6/eudistomin U; 64297-64-9/2-iodoxybenzoic acid
Comments/Corrections

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