Document Detail


Roles of pancreatic polypeptide in regulation of food intake.
MedLine Citation:
PMID:  11825646     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Pancreatic polypeptide (PP) is produced in pancreatic islets of Langerhans and released into the circulation after ingestion of a meal. Peripherally administered PP suppresses food intake and gastric emptying. On the other hand, central administration of PP elicits food intake and gastric emptying. Therefore, PP actions on food intake may be, in part, attributable to gastric emptying. PP transgenic mice exhibit decreases in both food intake and gastric emptying rate that were clearly reversed by anti-PP antiserum. PP is an anorexigenic signal in the periphery and an orexigenic signal in the central nervous system.
Authors:
Goro Katsuura; Akihiro Asakawa; Akio Inui
Related Documents :
12374716 - The lma-proseal is an effective alternative to tracheal intubation for laparoscopic cho...
25272576 - Evaluating adult dietary intakes of nitrate and nitrite in polish households during 200...
15734296 - Effect of liquid volume and food intake on the absolute bioavailability of danazol, a p...
10608686 - Radiographic contrast gastrointestinal study of the neonatal llama.
8719736 - The effect of solvent treatment on the chemical composition and organoleptic acceptabil...
11736746 - Epidemiology of food allergy/food intolerance in adults: associations with other manife...
Publication Detail:
Type:  Journal Article; Review    
Journal Detail:
Title:  Peptides     Volume:  23     ISSN:  0196-9781     ISO Abbreviation:  Peptides     Publication Date:  2002 Feb 
Date Detail:
Created Date:  2002-02-04     Completed Date:  2002-05-06     Revised Date:  2005-11-16    
Medline Journal Info:
Nlm Unique ID:  8008690     Medline TA:  Peptides     Country:  United States    
Other Details:
Languages:  eng     Pagination:  323-9     Citation Subset:  IM    
Affiliation:
Aburahi Laboratories, Shionogi & Co. Ltd., Shiga, 520-3423 Japan.
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms
Descriptor/Qualifier:
Animals
Central Nervous System / metabolism
Dose-Response Relationship, Drug
Feeding Behavior / drug effects
Gastric Emptying / drug effects*
Mice
Mice, Transgenic
Pancreatic Polypeptide / metabolism*,  physiology*
Time Factors
Chemical
Reg. No./Substance:
59763-91-6/Pancreatic Polypeptide

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


Previous Document:  Structure and receptor binding of PYY analogs.
Next Document:  Pancreatic polypeptide in pancreatitis.