Document Detail


Roles of different areas of palatine bone denudation on growth and development of the maxilla and dental arch: an experimental study.
MedLine Citation:
PMID:  17414291     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
This study was designed to explore the relationship of the growth of the maxilla and dental arch with different sizes of the denudation area on the hard palate. We tested the hypothesis that different sizes of denudation areas on the hard palate following palatoplasty would significantly influence the growth of the maxilla and dental arch differently. Fifty-one three-week-old Sprague-Dawley male rats were randomly divided into a control group and 3 experimental groups. In the three experimental groups, bilateral palatal mucoperiosteum was excised to three different proportions, i.e. one-quarter, one-half and three-quarters of the palate. Then, the animals were sequentially injected weekly with different fluorescent markers alternately. Three in each group were sacrificed randomly every two weeks with maxilla dissected following injections. The widths of the maxilla and dental arch were measured and the fluorescent labeling investigated at different phases. The results showed that the growth of the maxilla and dental arch here was inversely correlated with the area of denuded bone on palate. Therefore, our data may provide references for optimal treatment of cleft palate.
Authors:
Tian Meng; Bing Shi; Xu Huang; Qian Zheng; Yan Wang; Min Wu; Yong Lu; Sheng Li
Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  The Journal of craniofacial surgery     Volume:  18     ISSN:  1049-2275     ISO Abbreviation:  J Craniofac Surg     Publication Date:  2007 Mar 
Date Detail:
Created Date:  2007-04-06     Completed Date:  2007-05-29     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  9010410     Medline TA:  J Craniofac Surg     Country:  United States    
Other Details:
Languages:  eng     Pagination:  391-8     Citation Subset:  D    
Affiliation:
Department of Oral and Maxillofacial Surgery, West China College of Stomatology, Sichuan University, Chengdu, People's Republic of China.
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MeSH Terms
Descriptor/Qualifier:
Animals
Dental Arch / growth & development*
Fluorescent Dyes
Male
Maxilla / growth & development*
Mouth Mucosa / surgery
Osteogenesis / physiology*
Palate, Hard / surgery*
Periosteum / surgery
Rats
Rats, Sprague-Dawley
Chemical
Reg. No./Substance:
0/Fluorescent Dyes

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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