Document Detail

Role of ultrasonography in early gestation in the diagnosis of congenital heart defects.
MedLine Citation:
PMID:  20427794     Owner:  NLM     Status:  MEDLINE    
OBJECTIVE: The purpose of this series was to determine the sensitivity of ultrasonography in early gestation (UEG) using nuchal translucency (NT) and the 4-chamber view (4CV) in the early diagnosis of congenital heart defects (CHDs). METHODS: This was a retrospective chart review of all patients presenting for UEG between 2002 and 2009. At our center, a survey of fetal anatomy is performed at the time of the NT assessment at 11 weeks to 13 weeks 6 days. A second-trimester scan (STS) is done at 20 to 23 weeks and a third-trimester scan at 32 to 35 weeks. Suspected cases of CHDs were evaluated by a pediatric cardiologist. All neonates were examined at birth by a pediatrician, and when clinically indicated, fetal echocardiography was performed. RESULTS: A total of 1370 fetuses were scanned. Congenital heart defects were identified in 8 (0.6%). Nuchal translucency was above the 95th percentile for gestational age (GA) in 6 of 8, and the 4CV was abnormal in 6 of 8. Ultrasonography in early gestation detected 75% fetuses with CHDs, and 25% were detected by an STS. CONCLUSIONS: Our study emphasizes the importance of UEG in the detection of CHDs. In this small unselected low-risk population, UEG detected 75% of CHDs. Nuchal translucency was above the 95th percentile for GA, the 4CV was abnormal, or both in all 8 cases with CHDs.
Reem S Abu-Rustum; Linda Daou; Sameer E Abu-Rustum
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Journal of ultrasound in medicine : official journal of the American Institute of Ultrasound in Medicine     Volume:  29     ISSN:  1550-9613     ISO Abbreviation:  J Ultrasound Med     Publication Date:  2010 May 
Date Detail:
Created Date:  2010-04-29     Completed Date:  2010-08-04     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  8211547     Medline TA:  J Ultrasound Med     Country:  United States    
Other Details:
Languages:  eng     Pagination:  817-21     Citation Subset:  IM    
Center for Advanced Fetal Care, Najah Center, Tripoli, Lebanon.
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MeSH Terms
Gestational Age
Heart Defects, Congenital / ultrasonography*
Reproducibility of Results
Sensitivity and Specificity
Ultrasonography, Prenatal / methods*

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