| Role of two-way airflow owing to temperature difference in severe acute respiratory syndrome transmission: revisiting the largest nosocomial severe acute respiratory syndrome outbreak in Hong Kong. | |
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MedLine Citation:
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PMID: 21068029 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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By revisiting the air distribution and bioaerosol dispersion in Ward 8A where the largest nosocomial severe acute respiratory syndrome (SARS) outbreak occurred in Hong Kong in 2003, we found an interesting phenomenon. Although all the cubicles were in 'positive pressure' towards the corridor, the virus-containing bioaerosols generated from the index patient's cubicle were still transmitted to other cubicles, which cannot be explained in a traditional manner. A multi-zone model combining the two-way airflow effect was used to analyse this phenomenon. The multi-zone airflow model was evaluated by our experimental data. Comparing with the previous computational fluid dynamic simulation results, we found that the air exchange owing to the small temperature differences between cubicles played a major role in SARS transmission. Additionally, the validated multi-zone model combining the two-way airflow effect could simulate the pollutant transport with reasonable accuracy but much less computational time. A probable improvement in general ward design was also proposed. |
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Authors:
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Chun Chen; Bin Zhao; Xudong Yang; Yuguo Li |
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Publication Detail:
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Type: Journal Article; Research Support, Non-U.S. Gov't Date: 2010-11-10 |
Journal Detail:
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Title: Journal of the Royal Society, Interface / the Royal Society Volume: 8 ISSN: 1742-5662 ISO Abbreviation: J R Soc Interface Publication Date: 2011 May |
Date Detail:
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Created Date: 2011-03-23 Completed Date: 2011-07-15 Revised Date: 2012-05-08 |
Medline Journal Info:
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Nlm Unique ID: 101217269 Medline TA: J R Soc Interface Country: England |
Other Details:
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Languages: eng Pagination: 699-710 Citation Subset: IM |
Affiliation:
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Department of Building Science, School of Architecture, Tsinghua University, Beijing, People's Republic of China. |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Aerosols Air Movements Computer Simulation Cross Infection / diagnosis, transmission* Data Interpretation, Statistical Disease Outbreaks Facility Design and Construction Hong Kong Hospitals Humans Models, Statistical Severe Acute Respiratory Syndrome / diagnosis, transmission* Temperature Ventilation* |
| Chemical | |
Reg. No./Substance:
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0/Aerosols |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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