Document Detail

Role of transcranial Doppler in optimizing treatment of cerebral vasospasm in subarachnoid hemorrhage.
MedLine Citation:
PMID:  18480082     Owner:  NLM     Status:  MEDLINE    
This study was undertaken to evaluate the role of transcranial Doppler ultrasonography in arterial blood pressure management during hypervolemia/hypertension/ hemodilution therapy in patients with vasospasm from subarachnoid hemorrhage and correlate this data with neurologic outcome. The study included 18 adult patients, Hunt and Hess grades III-IV. Complete neurologic assessment was performed. Transcranial Doppler indices were calculated by standard formulas. On the basis of our results, resistance area product can be used to estimate the optimal arterial blood pressure in hypervolemia/hypertension/hemodilution therapy. An increase in the cerebral blood flow index was associated with better performance on neurologic examination. Estimated cerebral perfusion pressure from transcranial Doppler data analysis showed poor correlation with cerebral perfusion pressure derived from direct measurement of intracranial pressure in patients with cerebral vasospasm (rho = 0.15; 95% CI, 0.11-0.39; P = .2590).
Ribal S Darwish; Edward Ahn; Nana S Amiridze
Publication Detail:
Type:  Journal Article     Date:  2008-05-13
Journal Detail:
Title:  Journal of intensive care medicine     Volume:  23     ISSN:  0885-0666     ISO Abbreviation:  J Intensive Care Med     Publication Date:    2008 Jul-Aug
Date Detail:
Created Date:  2008-07-24     Completed Date:  2008-12-11     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  8610344     Medline TA:  J Intensive Care Med     Country:  United States    
Other Details:
Languages:  eng     Pagination:  263-7     Citation Subset:  IM    
Department of Anesthesiology, Critical Care Medicine, University of Maryland Medical Center, Baltimore, Maryland 21201-1595, USA.
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MeSH Terms
Aged, 80 and over
Blood Pressure
Cerebrovascular Circulation
Intracranial Pressure
Middle Aged
Subarachnoid Hemorrhage / complications*
Ultrasonography, Doppler, Transcranial*
Vasospasm, Intracranial / etiology,  physiopathology,  therapy*

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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