| Role of surgery in the management of Graves' disease. | |
| | |
MedLine Citation:
|
PMID: 11676109 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
|
Seventy-two patients, 50 women and 22 men, were operated on for Graves' disease. Their median age was 35 years. The indications for surgery included patients with large goitre, relapse after antithyroid drug (ATD) therapy, allergic reactions to ATD, non-compliance and finally an associated nodule with suspicion of carcinoma. Patients were rendered euthyroid with ATD before surgery and were pretreated with Lugol's iodine. Standard subtotal thyroidectomy was performed in 64 patients, total thyroidectomy in 7 patients, and one patient underwent a completion thyroidectomy after an initial subtotal thyroidectomy. The weight of the thyroid remnant on either side was estimated emperically between 3 g and 5 g. There was no postoperative death or thyrotoxic crisis. There was no case of permanent recurrent laryngeal nerve damage or hypoparathyroidism. Eight patients (11.1%) had temporary unilateral vocal cord palsy and 4 patients (5.5%) had temporary hypocalcemia. One patient (1.4%) developed recurrent hyperthyroidism. Postoperative transient hypothyroidism developed in 87.5% cases, all within the first postoperative year. The functional results at 2 years were as follows: Out of 47 cases followed 31 patients (65.9%) became euthyroid while 15 (31.9%) were still hypothyroid and requited long term substitutive treatment. Ophthalmopathy worsened in only one patient. Thyroidectomy has reasonable role in the management of Graves' disease, because the patients have had their diseases rapidly terminated, were hospitalised for an average period of only 3.5 days and have had no permanent functional insult except for hypothyroidism. |
| | |
Authors:
|
A Agarwal; S K Mishra |
Related Documents
:
|
2741719 - Extended long-term drug monotherapy of graves' disease. 12100079 - Does radioiodine therapy have disadvantageous effects in non-iodine accumulating differ... 20435429 - Total parathyroidectomy without autotransplantation for the treatment of secondary hype... 12912749 - The significance of elevated levels of parathyroid hormone in patients with morbid obes... 15757849 - Effect of ultrasound-guided interstitial laser photocoagulation on benign solitary soli... 17188149 - Routine ipsilateral level vi lymphadenectomy reduces postoperative thyroglobulin levels... 16317969 - Effectiveness and safety of tooth bleaching in teenagers. 20590499 - Use of a modified vinsot technique for partial phallectomy in 11 standing horses. 19603229 - Healing of stoma orifices: multicenter, prospective, randomized study comparing calcium... |
Publication Detail:
|
Type: Journal Article |
Journal Detail:
|
Title: Journal of the Indian Medical Association Volume: 99 ISSN: 0019-5847 ISO Abbreviation: J Indian Med Assoc Publication Date: 2001 May |
Date Detail:
|
Created Date: 2001-10-24 Completed Date: 2001-12-04 Revised Date: 2005-11-17 |
Medline Journal Info:
|
Nlm Unique ID: 7505608 Medline TA: J Indian Med Assoc Country: India |
Other Details:
|
Languages: eng Pagination: 252, 254-6 Citation Subset: IM |
Affiliation:
|
Department of Endocrine Surgery, Sanjay Gandhi Postgraduate Institute of Medical Sciences, Lucknow. |
Export Citation:
|
APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
|
Adolescent Adult Female Graves Disease / surgery* Humans Hypothyroidism / etiology Male Middle Aged Thyroidectomy* / adverse effects |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
Previous Document: Role of destructive operations in modern day obstetrics.
Next Document: Diabetic care in general practice--a survey.