Document Detail


Role of sodium reduction in the treatment and prevention of hypertension.
MedLine Citation:
PMID:  9192491     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Evidence relating dietary sodium and blood pressure comes from a variety of sources: animal experiments, observational epidemiologic studies, migration studies, and randomized controlled trials. In this review, we examine new findings in each of these areas published during 1995 and 1996. Results from both observational epidemiologic studies and randomized controlled trials demonstrated a dose-response association between dietary sodium and blood pressure in humans. The relationship of dietary sodium to blood pressure was modified by age, race, body weight, and initial level of blood pressure. On average, a 100-mmol decrease in urinary sodium was associated with a reduction of approximately 3 mm Hg in systolic and a 2 mm Hg in diastolic blood pressure. In a general population, this blood pressure reduction would substantially reduce the societal burden of cardiovascular and renal diseases.
Authors:
J He; P K Whelton
Publication Detail:
Type:  Journal Article; Review    
Journal Detail:
Title:  Current opinion in cardiology     Volume:  12     ISSN:  0268-4705     ISO Abbreviation:  Curr. Opin. Cardiol.     Publication Date:  1997 Mar 
Date Detail:
Created Date:  1997-08-07     Completed Date:  1997-08-07     Revised Date:  2006-05-04    
Medline Journal Info:
Nlm Unique ID:  8608087     Medline TA:  Curr Opin Cardiol     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  202-7     Citation Subset:  IM    
Affiliation:
Tulane University School of Public Health and Tropical Medicine, New Orleans, LA 70112, USA.
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MeSH Terms
Descriptor/Qualifier:
Animals
Blood Pressure
Diet, Sodium-Restricted*
Emigration and Immigration
Humans
Hypertension / diet therapy*,  epidemiology,  prevention & control*
Morbidity
Observation
Sodium / urine
Chemical
Reg. No./Substance:
7440-23-5/Sodium

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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