Document Detail


Role of resynchronisation therapy and implantable cardioverter defibrillators in heart failure.
MedLine Citation:
PMID:  16397075     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
The worldwide prevalence of heart failure is increasing in part because of an aging population. In the developed world, heart failure affects 1%-2% of the general population, accounting for 5% of adult hospital admissions. There is now convincing evidence supporting the beneficial effects of cardiac resynchronisation therapy for the treatment of heart failure. Numerous observational studies, as well as a series of randomised controlled trials, have shown the safety, efficacy, and long term benefits for patients with chronic systolic heart failure who have broad QRS complexes and refractory symptoms despite optimal medical therapy. These studies have consistently found statistically significant improvements in quality of life, New York Heart Association functional class, exercise tolerance, and left ventricular reverse remodelling. Recent evidence suggests that the benefit may at least in part be because of a reduction in mechanical dysynchrony.
Authors:
S Ellery; L Williams; M Frenneaux
Related Documents :
20118395 - Chronic heart failure: contemporary diagnosis and management.
16036035 - Quality of care and outcomes in acute decompensated heart failure: the adhere registry.
2961425 - Responses of vasoactive hormones in congestive cardiac failure.
9366285 - The progression from hypertension to heart failure.
7073365 - Myocardial protection with cold blood potassium cardioplegia during prolonged aortic cr...
11747815 - A defect in the kv channel-interacting protein 2 (kchip2) gene leads to a complete loss...
Publication Detail:
Type:  Journal Article; Review    
Journal Detail:
Title:  Postgraduate medical journal     Volume:  82     ISSN:  1469-0756     ISO Abbreviation:  Postgrad Med J     Publication Date:  2006 Jan 
Date Detail:
Created Date:  2006-01-06     Completed Date:  2006-07-21     Revised Date:  2013-06-07    
Medline Journal Info:
Nlm Unique ID:  0234135     Medline TA:  Postgrad Med J     Country:  England    
Other Details:
Languages:  eng     Pagination:  16-23     Citation Subset:  IM    
Affiliation:
Department of Cardiovascular Medicine, University of Birmingham, Edgbaston, Birmingham B15 2TT, UK.
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms
Descriptor/Qualifier:
Cardiac Pacing, Artificial / methods*
Defibrillators, Implantable*
Heart Failure / therapy*
Humans
Mitral Valve Insufficiency / prevention & control
Pacemaker, Artificial*
Ventricular Remodeling
Comments/Corrections

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


Previous Document:  Ethnic variations in the management of patients with acute stroke.
Next Document:  Growth hormone and its disorders.