Document Detail


Role of respiratory and non-respiratory neurones in the region of the NTS in the elaboration of the sneeze reflex in cat.
MedLine Citation:
PMID:  9369303     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Extracellular recordings were made in the dorsal respiratory group (DRG) and adjacent reticular formation following single-shock stimulation of the anterior ethmoidal nerve (AEN) and during sneeze evoked by repetitive stimulation of the AEN in nembutal-anaesthetized, curarized and ventilated cats. These neurones were characterised according to (i) their activity during the respiratory cycle (as inspiratory augmenting or decrementing (I Aug or I Dec), expiratory augmenting or decrementing (E Aug or E Dec), silent or tonic), and (ii) their axonal projection (bulbospinal or non-bulbospinal-non-vagal (BS or NBS-NV)). Following single-shock stimulation of the AEN, most of the inspiratory neurones were transiently inhibited, whereas E Aug neurones were activated and E Dec neurones were activated and then inhibited. Silent neurones responded with a multispike or a paucispike pattern. Following repetitive stimulation of the AEN and during the resulting sneeze reflex, I Aug neurones increased their activity in parallel with the phrenic activity, I Dec neurones fired at the onset and at the end of the inspiration, E Dec and some silent neurones fired either during the compressive phase or after the expulsive phase, whereas E Aug and some silent neurones fired during the expulsive phase. We conclude that sneeze involves a reconfiguration of the central respiratory drive which uses, at least partly, the respiratory network to trigger a non-ventilatory defensive motor act.
Authors:
F Wallois; L Bodineau; J M Macron; D Marlot; B Duron
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Brain research     Volume:  768     ISSN:  0006-8993     ISO Abbreviation:  Brain Res.     Publication Date:  1997 Sep 
Date Detail:
Created Date:  1997-12-18     Completed Date:  1997-12-18     Revised Date:  2003-11-14    
Medline Journal Info:
Nlm Unique ID:  0045503     Medline TA:  Brain Res     Country:  NETHERLANDS    
Other Details:
Languages:  eng     Pagination:  71-85     Citation Subset:  IM    
Affiliation:
URA CNRS 1331, Laboratoire de Neurophysiologie, Faculté de Médecine, Université de Picardie, Amiens, France.
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MeSH Terms
Descriptor/Qualifier:
Animals
Cats
Electric Stimulation
Female
Male
Neurons / physiology*
Phrenic Nerve / physiology
Reflex / physiology*
Respiratory System / innervation*
Sneezing / physiology*
Solitary Nucleus / cytology,  physiology*
Spinal Cord / cytology,  physiology*
Vagus Nerve / physiology

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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