Document Detail

Role of perceptive threshold in myocardial infarction patients without previous angina.
MedLine Citation:
PMID:  2046137     Owner:  NLM     Status:  MEDLINE    
The purpose of this study is to clarify the mechanism of sudden onset myocardial infarction (MI) without previous angina and the relationship of MI without previous angina to the mechanism of onset of postinfarction asymptomatic myocardial ischemia. The mean initial time of ischemic pain in the upper arm under the tourniquet test was significantly prolonged in the MI patients without previous angina, compared with that for the MI patients with previous angina and normal control subjects, although there are some overlapping cases (74 +/- 37 sec versus 52 +/- 20 sec (p less than 0.01), and versus 56 +/- 15 sec (p less than 0.05), respectively). The tolerance time for ischemic pain also was similarly prolonged. There was no significant difference between the groups of MI patients (with and without previous angina) with respect to age, frequency of complications of diabetes mellitus, severity of coronary artery lesions or site of MI. The incidence of post-infarction myocardial ischemia was 50% for the previous angina group and 39.5% for the group without previous angina, but the frequency of asymptomatic ischemia was significantly higher in patients without previous angina, at 66.7%, than in those with previous angina, 32.3% (p less than 0.05). These results suggest that there is a close relationship between the mechanism of MI with sudden onset and that of asymptomatic myocardial ischemia during the pre- and post-infarction periods in patients with low sensitivity to pain.
N Fukuma; H Kishida; H Okumura
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Publication Detail:
Type:  Comparative Study; Journal Article    
Journal Detail:
Title:  Japanese circulation journal     Volume:  55     ISSN:  0047-1828     ISO Abbreviation:  Jpn. Circ. J.     Publication Date:  1991 Apr 
Date Detail:
Created Date:  1991-07-12     Completed Date:  1991-07-12     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  7806868     Medline TA:  Jpn Circ J     Country:  JAPAN    
Other Details:
Languages:  eng     Pagination:  316-23     Citation Subset:  IM    
First Department of Internal Medicine, Nippon Medical School, Tokyo, Japan.
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MeSH Terms
Angina Pectoris / physiopathology
Coronary Disease / etiology,  physiopathology
Middle Aged
Myocardial Infarction / physiopathology*
Pain / physiopathology*
Sensory Thresholds*
Time Factors

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