Document Detail

Role of mediastinoscopy in the diagnosis of mediastinal masses.
MedLine Citation:
PMID:  2355386     Owner:  NLM     Status:  MEDLINE    
In order to assess the diagnostic efficiency of mediastinoscopy in patients with undiagnosed mediastinal masses, a retrospective review was undertaken of the results obtained in a consecutive series of 42 patients presenting over a 5-year period. In 28 (67%) patients, a tissue diagnosis was made. Ten (24%) patients underwent a negative mediastinoscopy but were found to have significant pathology on further investigation (eight in a location outside the range of conventional mediastinoscopy). Four (10%) patients had negative findings and were confirmed to have no significant pathology on further investigation and follow-up. Overall, mediastinoscopy had a sensitivity of 74%, a specificity of 100% and an accuracy of 76%; however, for lesions within the range of mediastinoscopy, the sensitivity was 93%, the specificity 100% and the accuracy 94%. The predictive value of a negative examination was 66%. Mediastinoscopy is a valuable technique in the diagnosis of mediastinal masses but, because of the low predictive value of a negative examination, further evaluation, including thoracotomy if necessary, is still indicated if mediastinoscopy is unhelpful.
A R Naylor; R C Elliott; W S Walker; D Lamb; E W Cameron; J Dark
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Journal of the Royal College of Surgeons of Edinburgh     Volume:  35     ISSN:  0035-8835     ISO Abbreviation:  J R Coll Surg Edinb     Publication Date:  1990 Apr 
Date Detail:
Created Date:  1990-07-25     Completed Date:  1990-07-25     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  7503110     Medline TA:  J R Coll Surg Edinb     Country:  SCOTLAND    
Other Details:
Languages:  eng     Pagination:  98-100     Citation Subset:  IM    
Department of Thoracic Surgery, City Hospital, Edinburgh, UK.
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MeSH Terms
Mediastinal Diseases / diagnosis*
Mediastinal Neoplasms / diagnosis
Middle Aged

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