Document Detail


Role of magnesium sulphate in the treatment of hypomagnesaemia in eclamptic patients.
MedLine Citation:
PMID:  21522096     Owner:  NLM     Status:  In-Data-Review    
Abstract/OtherAbstract:
Hypomagnasaemia has been identified as one of the main causes of eclampsia and preeclampsia which causes maternal and fetal/neonatal morbidity and mortality. In spite of wide difference of opinion about the best anticonvulsant, magnesium sulphate, diazepam and phenytoin are currently the mostly widely used anticonvulsants. The present study tried to find out the role of MgSO4 in correcting hypomagnasaemia in eclamptic women in Bangladesh. The study included 60 healthy (non eclamptic) 60 eclamptic women and was carried out in two hospitals of Dhaka city, during January 1999 to June 2000. Required tests were done in the Department of Biochemistry, BSMMU. Comparison of pretreatment clinical parameters between the two study groups showed highly significant (p<0.001) differences, MgSO4 level, pulse rate, systolic and diastolic blood pressure, and respiratory rate. After the case group of women was treated with MgSO4, the clinical parameters, pulse rate, systolic and diastolic blood pressure, and respiratory rate, between control and case groups showed no significant differences. However, serum magnesium level in case group increased to 3.41±0.21 mg/dl from pretreatment level of 1.02±0.26 mg/dl, and when compared to control (2.25±0.26 mg/dl), the increase was highly significant (p<0.001). It may be concluded that correction of hypomagnesemia may help to improve eclamptic situation.
Authors:
S A Anwary; M Alfazzaman; M R Islam
Related Documents :
15614026 - Single nucleotide polymorphisms predict the change in left ventricular mass in response...
20160196 - Confirmation that the renin gene distal enhancer polymorphism ren-5312c/t is associated...
9931116 - Tgf-beta1 dna polymorphisms, protein levels, and blood pressure.
18544576 - A variant of the igf-i gene is associated with blood pressure but not with left heart d...
22783816 - Non-dipping pattern in untreated hypertensive patients is related to increased pulse wa...
16095176 - Accuracy of indirect measurement of blood pressure in neonatal foals.
Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Mymensingh medical journal : MMJ     Volume:  20     ISSN:  1022-4742     ISO Abbreviation:  Mymensingh Med J     Publication Date:  2011 Apr 
Date Detail:
Created Date:  2011-04-27     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  9601799     Medline TA:  Mymensingh Med J     Country:  Bangladesh    
Other Details:
Languages:  eng     Pagination:  252-6     Citation Subset:  IM    
Affiliation:
Dr Shaheen Ara Anwary, Assistant Professor, Department of Obstetrics and Gynaecology, Bangabandhu Sheikh Mujib Medical University, Dhaka, Bangladesh.
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms
Descriptor/Qualifier:

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


Previous Document:  Human Rabies among the Paediatric Population in Bangladesh.
Next Document:  Role of oral clonidine on intraopereative haemodynamic stability for craniotomies of intracranial sp...