Document Detail

Role of leuprolide acetate depot in hysteroscopic surgery: a controlled study.
MedLine Citation:
PMID:  8458448     Owner:  NLM     Status:  MEDLINE    
OBJECTIVE: To evaluate leuprolide acetate (LA) depot (Enantone Depot, Takeda, Italy) when administered preoperatively in hysteroscopic surgery. DESIGN: Prospective, comparative study. SETTING: University Clinic of Obstetrics and Gynecology. PATIENTS: One hundred ninety-three patients (114 pretreated with LA depot and 79 controls) who underwent hysteroscopic surgery for uterine septa (group A), submucous fibroids (group B), and abnormal uterine bleeding (group C). RESULTS: In groups B and C there was a significant reduction in the operating time, bleeding during the operation, and the amount of distention medium required after LA depot administration, but no significant differences in surgical feasibility or efficacy were found in group A patients after treatment. CONCLUSION: Preoperative treatment with LA depot is effective in making hysteroscopic surgery easier.
A Perino; N Chianchiano; M Petronio; E Cittadini
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Publication Detail:
Type:  Clinical Trial; Controlled Clinical Trial; Journal Article    
Journal Detail:
Title:  Fertility and sterility     Volume:  59     ISSN:  0015-0282     ISO Abbreviation:  Fertil. Steril.     Publication Date:  1993 Mar 
Date Detail:
Created Date:  1993-04-23     Completed Date:  1993-04-23     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  0372772     Medline TA:  Fertil Steril     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  507-10     Citation Subset:  IM    
Cattedra di Fisiopatologia della Riproduzione Umana, University of Palermo, Italy.
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MeSH Terms
Delayed-Action Preparations
Endometrium / surgery
Leuprolide / administration & dosage,  adverse effects,  therapeutic use*
Myometrium / surgery
Prospective Studies
Uterine Hemorrhage / surgery
Uterine Neoplasms / surgery
Uterus / surgery*
Reg. No./Substance:
0/Delayed-Action Preparations; 53714-56-0/Leuprolide

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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