Document Detail

Role of inferior rectus botulinum toxin injection in iatrogenic vertical strabismus.
MedLine Citation:
PMID:  21635164     Owner:  NLM     Status:  In-Data-Review    
Introduction: We describe the uses and effectiveness of botulinum toxin to the inferior rectus muscle in iatrogenic vertical strabismus. Methods: A retrospective review of our database to identify patients who had undergone inferior rectus botulinum toxin injection between 1982 and 2006 for iatrogenic vertical strabismus. Results: There were 13 patients, 5 female, with an age range of 14 to 78 years. Eight left eyes were injected. The mean period of follow-up was 3.3 years. Etiologies included post-local anesthetic, post-plaque radiotherapy for malignant melanoma, adherence syndrome after inferior oblique surgery, and post-botulinum toxin to the levator muscle to produce a temporary therapeutic ptosis. Reversal on first injection occurred in 7 patients and occurred in a further 2 patients on second injection. Pre-injection binocularity was not demonstrable in 3 patients; 2 of these patients did have binocular vision demonstrable after botulinum toxin injection. Seven patients had one injection, 3 patients had two, 1 had three, 1 had five, and 1 had six. Discussion: The data demonstrate the range of indications that can be successfully treated and managed with inferior rectus botulinum toxin injection in iatrogenic vertical strabismus.
John-Sebastian Barry; Emma Lm Dawson; Gillian Gw Adams; John P Lee
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Strabismus     Volume:  19     ISSN:  1744-5132     ISO Abbreviation:  Strabismus     Publication Date:  2011 Jun 
Date Detail:
Created Date:  2011-06-03     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  9310896     Medline TA:  Strabismus     Country:  England    
Other Details:
Languages:  eng     Pagination:  38-42     Citation Subset:  IM    
Moorfields Eye Hospital, London.
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