Document Detail


Role of hypothalamic neurogenesis in feeding regulation.
MedLine Citation:
PMID:  24231724     Owner:  NLM     Status:  Publisher    
Abstract/OtherAbstract:
The recently described generation of new neurons in the adult hypothalamus, the center for energy regulation, suggests that hypothalamic neurogenesis is a crucial part of the mechanisms that regulate food intake. Accordingly, neurogenesis in both the adult and embryonic hypothalamus is affected by nutritional cues and metabolic disorders such as obesity, with consequent effects on energy-balance. This review critically discusses recent findings on the contribution of adult hypothalamic neurogenesis to feeding regulation, the impact of energy-balance disorders on adult hypothalamic neurogenesis, and the influence of embryonic hypothalamic neurogenesis upon feeding regulation in the adult. Understanding how hypothalamic neurogenesis contributes to food intake control will change the paradigm on how we perceive energy-balance regulation.
Authors:
Lígia Sousa-Ferreira; Luís Pereira de Almeida; Cláudia Cavadas
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Publication Detail:
Type:  JOURNAL ARTICLE     Date:  2013-11-12
Journal Detail:
Title:  Trends in endocrinology and metabolism: TEM     Volume:  -     ISSN:  1879-3061     ISO Abbreviation:  Trends Endocrinol. Metab.     Publication Date:  2013 Nov 
Date Detail:
Created Date:  2013-11-15     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  9001516     Medline TA:  Trends Endocrinol Metab     Country:  -    
Other Details:
Languages:  ENG     Pagination:  -     Citation Subset:  -    
Copyright Information:
Copyright © 2013 Elsevier Ltd. All rights reserved.
Affiliation:
Center for Neuroscience and Cell Biology (CNC), University of Coimbra, 3004-517 Coimbra, Portugal.
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