| Role of high frequency ultrasonography in the evaluation of palpable breast masses in Chinese women: alternative to mammography? | |
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MedLine Citation:
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PMID: 8866446 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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We prospectively assessed the accuracy of high resolution breast ultrasonography in the diagnosis of palpable breast masses in comparison to clinical palpation and x-ray mammography. Four hundred and eight Chinese women with palpable breast lumps had clinical assessment followed by ultrasonography of the breast, mammography (for women over 35 years), and fine needle aspiration cytology. Excisional biopsy or surgery was performed for suggestive lesions. The clinical, mammographic and ultrasound diagnoses were compared with the final pathologic diagnosis. In the determination of whether a lesion was malignant, the sensitivity, specificity, and positive predictive values were 97%, 97%, and 85%, respectively, for ultrasonography; 92%, 94%, and 84%, respectively, for mammography; and 88%, 92%, and 67%, respectively, for clinical evaluation. The specificity for combined clinical palpation and ultrasonography was higher (99%) than that for combined clinical palpation and mammography (96%). Addition of ultrasonography to combined clinical palpation and mammography increased specificity. Mammography in addition to combined clinical palpation and ultrasonography did not significantly improve the sensitivity, specificity, or positive predictive value. This limited usefulness raises the question as to whether it should be eliminated in the workup of a palpable mass in the average Chinese patient. Its main advantage is the detection of extended foci of carcinoma in situ related to a palpable mass, which often is undetected by ultrasonography. |
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Authors:
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W T Yang; C O Mok; W King; A Tang; C Metreweli |
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Publication Detail:
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Type: Comparative Study; Journal Article |
Journal Detail:
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Title: Journal of ultrasound in medicine : official journal of the American Institute of Ultrasound in Medicine Volume: 15 ISSN: 0278-4297 ISO Abbreviation: J Ultrasound Med Publication Date: 1996 Sep |
Date Detail:
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Created Date: 1997-01-21 Completed Date: 1997-01-21 Revised Date: 2006-11-15 |
Medline Journal Info:
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Nlm Unique ID: 8211547 Medline TA: J Ultrasound Med Country: UNITED STATES |
Other Details:
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Languages: eng Pagination: 637-44 Citation Subset: IM |
Affiliation:
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Department of Diagnostic Radiology, Chinese University of Hong Kong, Prince of Wales Hospital, Shatin, N.T., Hong Kong. |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Adult Age Distribution Biopsy, Needle Breast Diseases / epidemiology, pathology, radiography, ultrasonography* China / epidemiology False Positive Reactions Female Humans Mammography* / methods Middle Aged Palpation / methods* Predictive Value of Tests Prospective Studies Sensitivity and Specificity Ultrasonography, Mammary* |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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