Document Detail

Role of high frequency ultrasonography in the evaluation of palpable breast masses in Chinese women: alternative to mammography?
MedLine Citation:
PMID:  8866446     Owner:  NLM     Status:  MEDLINE    
We prospectively assessed the accuracy of high resolution breast ultrasonography in the diagnosis of palpable breast masses in comparison to clinical palpation and x-ray mammography. Four hundred and eight Chinese women with palpable breast lumps had clinical assessment followed by ultrasonography of the breast, mammography (for women over 35 years), and fine needle aspiration cytology. Excisional biopsy or surgery was performed for suggestive lesions. The clinical, mammographic and ultrasound diagnoses were compared with the final pathologic diagnosis. In the determination of whether a lesion was malignant, the sensitivity, specificity, and positive predictive values were 97%, 97%, and 85%, respectively, for ultrasonography; 92%, 94%, and 84%, respectively, for mammography; and 88%, 92%, and 67%, respectively, for clinical evaluation. The specificity for combined clinical palpation and ultrasonography was higher (99%) than that for combined clinical palpation and mammography (96%). Addition of ultrasonography to combined clinical palpation and mammography increased specificity. Mammography in addition to combined clinical palpation and ultrasonography did not significantly improve the sensitivity, specificity, or positive predictive value. This limited usefulness raises the question as to whether it should be eliminated in the workup of a palpable mass in the average Chinese patient. Its main advantage is the detection of extended foci of carcinoma in situ related to a palpable mass, which often is undetected by ultrasonography.
W T Yang; C O Mok; W King; A Tang; C Metreweli
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Publication Detail:
Type:  Comparative Study; Journal Article    
Journal Detail:
Title:  Journal of ultrasound in medicine : official journal of the American Institute of Ultrasound in Medicine     Volume:  15     ISSN:  0278-4297     ISO Abbreviation:  J Ultrasound Med     Publication Date:  1996 Sep 
Date Detail:
Created Date:  1997-01-21     Completed Date:  1997-01-21     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  8211547     Medline TA:  J Ultrasound Med     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  637-44     Citation Subset:  IM    
Department of Diagnostic Radiology, Chinese University of Hong Kong, Prince of Wales Hospital, Shatin, N.T., Hong Kong.
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MeSH Terms
Age Distribution
Biopsy, Needle
Breast Diseases / epidemiology,  pathology,  radiography,  ultrasonography*
China / epidemiology
False Positive Reactions
Mammography* / methods
Middle Aged
Palpation / methods*
Predictive Value of Tests
Prospective Studies
Sensitivity and Specificity
Ultrasonography, Mammary*

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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