Document Detail

Role of exercise training on pulmonary ischemia/reperfusion and inflammatory response.
MedLine Citation:
PMID:  20305929     Owner:  NLM     Status:  MEDLINE    
Advances in new technologies associated with improvement of knowledge in medicine have promoted important development in therapeutic and preventive approaches in an attempt to diminish complications following cardiothoracic process involving ischemia/ reperfusion (IR). Nevertheless, postoperative pulmonary injuries remain high and are considered one of the most frequent complications after cardiothoracic surgery. Thus, new strategies with prophylactic actions are crucial in cardiovascular area in an attempt to reduce complications and to improve patient life. It is well documented that exercise training is a non-pharmacological tool to prevent and/or treat cardiovascular and endocrine-metabolic diseases. The aim of this review was to provide an update of several studies pulmonary IR process and its local and systemic complications and the role of inflammatory response. Furthermore, this review focused on the effects of exercise training on the pulmonary IR as an important strategy to diminish its complications. This review shows that few studies exist regarding the health-promoting physical exercise in cardiothoracic surgery and how important is necessary to increase studies in this area. Recently, studies from our laboratory showed beneficial effects of exercise training in experimental model of pulmonary IR. Collectively, data show that physical preconditioning for patients is very important approach to reduce postsurgical complications as well as diminish the time of hospitalization which includes a specialized personal trainer in the health team. Moreover, this preventive strategy might improve patient recovery and would lead to consuming less resources of the health care system. This review included experimental studies in English and Portuguese found in SciELO and MEDLINE (from 1987 to 2008) and also classics texts related to the title.
Maria Andréia Delbin; Edson Antunes; Angelina Zanesco
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Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't; Review    
Journal Detail:
Title:  Revista brasileira de cirurgia cardiovascular : órgão oficial da Sociedade Brasileira de Cirurgia Cardiovascular     Volume:  24     ISSN:  1678-9741     ISO Abbreviation:  Rev Bras Cir Cardiovasc     Publication Date:    2009 Oct-Dec
Date Detail:
Created Date:  2010-03-22     Completed Date:  2010-07-30     Revised Date:  2012-04-02    
Medline Journal Info:
Nlm Unique ID:  9104279     Medline TA:  Rev Bras Cir Cardiovasc     Country:  Brazil    
Other Details:
Languages:  eng; por     Pagination:  552-61     Citation Subset:  IM    
Programa Pós-Graduação em Ciência da Motricidade, Departamento de Educação Física, Instituto de Biociência, Universidade Estadual Paulista Júlio de Mesquita Filho, Rio Claro, Brasil.
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MeSH Terms
Cardiac Surgical Procedures / adverse effects
Inflammation / physiopathology,  prevention & control*
Lung Diseases / etiology,  prevention & control*
Preoperative Care
Reperfusion Injury / etiology,  prevention & control*

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