Document Detail

Role of the early epithelium in the patterning of the teeth and Meckel's cartilage.
MedLine Citation:
PMID:  1812126     Owner:  NLM     Status:  MEDLINE    
Embryonic epithelium from the mandibular branchial arch organizes the dentition and the deposition of Meckel's cartilage. During 9-11 days of gestation mandibular arch epithelium can induce teeth in nondental ectomesenchyme in both mice and birds. In addition, the deposition of Meckel's cartilage as a rod of cartilage in the middle of the first branchial arch is under the control of the epithelium. The epithelium inhibits chondrogenesis; if it is removed, large amorphous masses of cartilage are found instead of the narrow rod typical of Meckel's cartilage.
E J Kollar; M Mina
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Publication Detail:
Type:  Comment; Journal Article; Research Support, U.S. Gov't, P.H.S.    
Journal Detail:
Title:  Journal of craniofacial genetics and developmental biology     Volume:  11     ISSN:  0270-4145     ISO Abbreviation:  J. Craniofac. Genet. Dev. Biol.     Publication Date:    1991 Oct-Dec
Date Detail:
Created Date:  1992-06-11     Completed Date:  1992-06-11     Revised Date:  2007-11-14    
Medline Journal Info:
Nlm Unique ID:  8109845     Medline TA:  J Craniofac Genet Dev Biol     Country:  DENMARK    
Other Details:
Languages:  eng     Pagination:  223-8     Citation Subset:  IM    
Department of BioStructure and Function, School of Dental Medicine, University of Connecticut Health Center, Farmington 06032.
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MeSH Terms
Cartilage / embryology
Collagen / biosynthesis
Epithelium / physiology*
Mandible / embryology*
Mesoderm / physiology
Tooth / embryology*
Grant Support
Reg. No./Substance:
Comment On:
J Craniofac Genet Dev Biol. 1991 Oct-Dec;11(4):326-37   [PMID:  1812133 ]
J Craniofac Genet Dev Biol. 1991 Oct-Dec;11(4):238-50   [PMID:  1812127 ]
J Craniofac Genet Dev Biol. 1991 Oct-Dec;11(4):192-213   [PMID:  1812125 ]
J Craniofac Genet Dev Biol. 1991 Oct-Dec;11(4):338-49   [PMID:  1725872 ]

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