| Role of dysautonomic symptoms in distinguishing Parkinson's disease (PD) from multiple system atrophy (MSA-P) within a year of developing motor symptoms. | |
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MedLine Citation:
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PMID: 21751644 Owner: NLM Status: In-Process |
Abstract/OtherAbstract:
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OBJECTIVE: Can dysautonomic symptoms occurring within a year of developing motor symptoms distinguish Multiple system atrophy-Parkinsonian (MSA-P) from Parkinson's disease (PD)? PATIENTS AND METHODS: Seventy-two Parkinsonian patients diagnosed as probable PD or MSA-P. RESULTS: PD (n = 58, 80.6%) and MSA (n = 14, 19.4%) patients were of similar age and had motor symptoms for similar duration. PD first presents with motor symptoms (68.3%) while MSA-P presents with dysautonomia (85.7%). Urinary incontinence was reported by MSA-P (64%) at their first visit and was absent in most PD (98%) patients. CONCLUSIONS: Urinary incontinence and orthostatic symptoms occurring in a parkinsonian patient within one-year history of motor symptoms suggests a diagnosis of MSA-P with high accuracy and their absence suggests PD. |
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Authors:
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Mona Ragothaman; Pazhayannur V Swaminath; Nagaraja Sarangmath; Suma Koshy; Mohan Adhyam; Dodaballapur K Subbakrishna; Christopher J Mathias; Uday B Muthane |
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Publication Detail:
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Type: Journal Article; Research Support, Non-U.S. Gov't |
Journal Detail:
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Title: The Journal of the Association of Physicians of India Volume: 59 ISSN: 0004-5772 ISO Abbreviation: J Assoc Physicians India Publication Date: 2011 Feb |
Date Detail:
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Created Date: 2011-07-14 Completed Date: - Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 7505585 Medline TA: J Assoc Physicians India Country: India |
Other Details:
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Languages: eng Pagination: 95-8 Citation Subset: IM |
Affiliation:
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Department of Neurology, National Institute of Mental Health and Neurosciences, Bangalore 560029, India. |
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| Grant Support | |
ID/Acronym/Agency:
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//Wellcome Trust |
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