| Role of dietary l-arginine supplementation on serum parameters and intestinal enzyme activities in rats fed an excess-fat diet. | |
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MedLine Citation:
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PMID: 16330176 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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We investigated whether dietary supplementation with L-arginine, the endogenous precursor of nitric oxide, might affect serum parameter levels body weight, food intake and activities of intestinal mucosa enzymes in animals fed with a standard diet or a diet high in saturated fat for 4 weeks. Body weight and food intake were not affected by diet but relative liver weight was higher in animals receiving a high-fat diet. Total cholesterol, LDL-cholesterol and triglyceride levels were higher in both groups fed high-fat diet and dietary L-arginine did not affect these parameters but produced an increase in serum protein levels and a slight decrease in glycaemia. Regarding the intestinal enzyme activities, rats fed a high-fat diet plus arginine showed the lowest intestinal disaccharidase activities. |
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Authors:
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M C Taboada; B Rodriguez; R Millán; I Míguez |
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Publication Detail:
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Type: Journal Article Date: 2005-10-27 |
Journal Detail:
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Title: Biomedicine & pharmacotherapy = Biomédecine & pharmacothérapie Volume: 60 ISSN: 0753-3322 ISO Abbreviation: Biomed. Pharmacother. Publication Date: 2006 Jan |
Date Detail:
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Created Date: 2005-12-26 Completed Date: 2007-03-20 Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 8213295 Medline TA: Biomed Pharmacother Country: France |
Other Details:
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Languages: eng Pagination: 10-3 Citation Subset: IM |
Affiliation:
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Department of Physiology, Faculty of Pharmacy, University of Santiago de Compostela, Spain. fftamac@usc.es |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Animals Arginine / administration & dosage, pharmacology* Blood Glucose / analysis Body Weight Dietary Fats Dietary Supplements* Disaccharidases / metabolism Eating Hyperlipidemias / blood*, etiology Intestinal Mucosa / drug effects*, metabolism Leucyl Aminopeptidase / metabolism Male Proteins / analysis Rats Rats, Sprague-Dawley |
| Chemical | |
Reg. No./Substance:
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0/Blood Glucose; 0/Dietary Fats; 0/Proteins; 74-79-3/Arginine; EC 3.2.1.-/Disaccharidases; EC 3.4.11.1/Leucyl Aminopeptidase |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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