Document Detail

Role of dietary habits in the development of esophageal cancer in Assam, the north-eastern region of India.
MedLine Citation:
PMID:  11759281     Owner:  NLM     Status:  MEDLINE    
The etiology of esophageal cancer remains largely unknown. In recent years, the role of dietary habits in the development of esophageal cancer has received much attention. Prevalence of esophageal cancer in Assam is highest among all the states of India. To identify the possible risk factors, a hospital-based case-control study was conducted with 502 cases and 1,004 controls. "Kalakhar," a unique and locally made food item, has emerged as a significant risk factor (odds ratio = 8.0, 95% confidence interval = 5.1-11.5, p < 0.001). Consumption of very spicy foods, hot foods and beverages, a diet containing high amounts of chili, and leftover food was positively associated with the risk of esophageal cancer. Green leafy vegetables and fruits were protective for esophageal cancer. The risk factors associated with consumption of locally prepared food items, e.g., kalakhar, and some dietary practices did not decrease, even after adjustments with different confounding factors. However, further studies are required to conclusively implicate these factors in causation of esophageal cancer.
R K Phukan; C K Chetia; M S Ali; J Mahanta
Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Nutrition and cancer     Volume:  39     ISSN:  0163-5581     ISO Abbreviation:  Nutr Cancer     Publication Date:  2001  
Date Detail:
Created Date:  2001-12-10     Completed Date:  2002-04-30     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  7905040     Medline TA:  Nutr Cancer     Country:  United States    
Other Details:
Languages:  eng     Pagination:  204-9     Citation Subset:  IM    
Regional Medical Research Centre, Indian Council of Medical Research, North-Eastern Region, Dibrugarh, Assam, India.
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MeSH Terms
Case-Control Studies
Dietary Proteins / administration & dosage
Educational Status
Esophageal Neoplasms / epidemiology,  etiology*,  prevention & control
Food Habits*
Food Preservation
Hydrogen-Ion Concentration
India / epidemiology
Risk Factors
Reg. No./Substance:
0/Dietary Proteins

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