Document Detail


Role of carcinoembryonic antigen, magnetic resonance imaging, and positron emission tomography-computed tomography in the evaluation of patients with suspected local recurrence of colorectal cancer.
MedLine Citation:
PMID:  21724118     Owner:  NLM     Status:  In-Data-Review    
Abstract/OtherAbstract:
The role of carcinoembryonic antigen (CEA), magnetic resonance imaging (MRI), and positron emission tomography (PET)-computed tomography (CT) in detection of local recurrence of colorectal cancer is evaluated in 71 patients, selected due to suspected relapse at CT follow-up. Recurrence was confirmed by histology in 18 cases and excluded in 25 cases. Sensitivity, specificity, positive and negative predictive values, and accuracy were as follows: 44.4%, 92.5%, 66.7%, 83.1%, and 80.3% for CEA; 88.9%, 73.6%, 53.3%, 95.1%, and 77.5% for MRI; and 94.4%, 73.6%, 54.8%, 97.5%, and 78.9% for PET-CT. A diagnostic protocol integrating CEA and dedicated imaging studies is to be advocated.
Authors:
Federica Fiocchi; Valentina Iotti; Guido Ligabue; Norma Malavasi; Gabriele Luppi; Bruno Bagni; Pietro Torricelli
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Clinical imaging     Volume:  35     ISSN:  1873-4499     ISO Abbreviation:  Clin Imaging     Publication Date:    2011 Jul-Aug
Date Detail:
Created Date:  2011-07-04     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  8911831     Medline TA:  Clin Imaging     Country:  United States    
Other Details:
Languages:  eng     Pagination:  266-73     Citation Subset:  IM    
Copyright Information:
Copyright © 2011 Elsevier Inc. All rights reserved.
Affiliation:
Dipartimento Integrato dei Servizi Diagnostici e per Immagine, Via del Pozzo 71, 41100 Modena, Italy.
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