Document Detail

Role of caloric restriction in the prolongation of life.
MedLine Citation:
PMID:  8556686     Owner:  NLM     Status:  MEDLINE    
Restriction of caloric intake increases longevity, slows the rate of functional decline, and reduces incidence of age-related disease in a variety of species. Most laboratory rodent studies have initiated restriction before puberty, whereas ongoing studies in nonhuman primates utilize restriction in adulthood. The mechanism of action of caloric restriction remains unknown; however, data suggest that cellular functions are altered in such a way that destructive by-products of metabolism are reduced, and defense or repair systems are enhanced by this nutritional manipulation.
R J McCarter
Related Documents :
1423856 - Reversal of food restriction-induced inhibition of mouse skin tumor promotion by adrena...
15814856 - Brief food restriction in old animals decreases triglyceride content and insulin-stimul...
6833976 - Effects of saltwater feeding and reduced food intake on femurs of domestic ducklings.
1812086 - Effect of riboflavin or pyridoxine deficiency on inflammatory response.
21653576 - An energy-dense, nutrient-poor dietary pattern is inversely associated with bone health...
8127886 - Expression and localization of amiloride-sensitive sodium channel indicate a role for n...
Publication Detail:
Type:  Journal Article; Research Support, U.S. Gov't, P.H.S.; Review    
Journal Detail:
Title:  Clinics in geriatric medicine     Volume:  11     ISSN:  0749-0690     ISO Abbreviation:  Clin. Geriatr. Med.     Publication Date:  1995 Nov 
Date Detail:
Created Date:  1996-02-28     Completed Date:  1996-02-28     Revised Date:  2007-11-14    
Medline Journal Info:
Nlm Unique ID:  8603766     Medline TA:  Clin Geriatr Med     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  553-65     Citation Subset:  IM    
Department of Physiology, University of Texas Health Science Center, San Antonio, USA.
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms
Aging / physiology
Cohort Studies
Diet, Reducing
Energy Intake / physiology*
Longevity / physiology*
Survival Analysis
Grant Support

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

Previous Document:  A comparative study on the self-care needs as perceived by women treated for depression
Next Document:  Diet, aging, and cancer.