Document Detail


Role of autologous lymphocyte cytotoxicity in colonic neoplasia.
MedLine Citation:
PMID:  6976915     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
The T-lymphocyte mediated killing of autologous carcinoma colon cells was investigated. There was no change in the incidence of activity with advanced disease, age, or nutritional status of the patient and no difference could be demonstrated in lymphocytes extracted from blood, draining lymph nodes, or the tumour itself. Nevertheless. T-lymphocyte activity did appear to be specific for the patients's own tumour, as it was rarely observed with allogeneic tumours. There was also no correlation with lymphocyte natural killer activity. The in vitro studies demonstrated patient specific T-lymphocyte activity in 23 of 47 patients with carcinoma of the colon, but the results do not correlate with clinical and pathological findings.
Authors:
P Gallagher; B M Vose; M Moore; P F Schofield
Related Documents :
25044045 - Epilepsy of infancy with migrating focal seizures: six patients treated with bromide.
7042775 - Antibody-dependent cellular cytotoxicity in bullous diseases.
1776975 - The effect of serum from patients with acute myocardial infarction on in vitro lymphocy...
54235 - E and eac rosetting lymphocytes in patients with carcinoma of bronchus. ii. a sequentia...
18512165 - Efficacy of nitric oxide in stroke - a randomized trial. characteristics of patients re...
23458935 - Prevalence of iron overload complications among patients with b-thalassemia major treat...
Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  Gut     Volume:  23     ISSN:  0017-5749     ISO Abbreviation:  Gut     Publication Date:  1982 Jan 
Date Detail:
Created Date:  1982-04-20     Completed Date:  1982-04-20     Revised Date:  2009-11-18    
Medline Journal Info:
Nlm Unique ID:  2985108R     Medline TA:  Gut     Country:  ENGLAND    
Other Details:
Languages:  eng     Pagination:  31-5     Citation Subset:  AIM; IM    
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms
Descriptor/Qualifier:
Adult
Aged
Cell Line
Colonic Neoplasms / immunology*,  pathology
Cytotoxicity, Immunologic*
Female
Humans
Lymph Nodes / immunology
Male
Middle Aged
T-Lymphocytes / immunology*
Comments/Corrections

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


Previous Document:  Immunological investigation in primary open angle glaucoma (author's transl)
Next Document:  Therapy in pulmonary histiocytosis X.