| Role of apoptosis in adverse ventricular remodeling. | |
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MedLine Citation:
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PMID: 22108728 Owner: NLM Status: In-Data-Review |
Abstract/OtherAbstract:
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Apoptosis is a key feature in the progression of heart disease. Stage B heart failure is characterized by a structurally abnormal heart in which the remodeled myocardium is prone to apoptosis. Elimination of the proapoptotic stimuli or inhibition of the apoptotic cascade could presumably rescue the myocardium and halt the progression of adverse remodeling and heart failure. In this article, the authors review the role of apoptosis (or programmed cell death) in determining the evolution of symptomatic heart failure and particularly the adverse remodeling in the aftermath of acute myocardial infarction. |
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Authors:
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Antonio Abbate; Jagat Narula |
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Publication Detail:
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Type: Journal Article |
Journal Detail:
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Title: Heart failure clinics Volume: 8 ISSN: 1551-7136 ISO Abbreviation: Heart Fail Clin Publication Date: 2012 Jan |
Date Detail:
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Created Date: 2011-11-23 Completed Date: - Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 101231934 Medline TA: Heart Fail Clin Country: United States |
Other Details:
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Languages: eng Pagination: 79-86 Citation Subset: IM |
Copyright Information:
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Copyright © 2012 Elsevier Inc. All rights reserved. |
Affiliation:
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VCU Pauley Heart Center, Virginia Commonwealth University, VCU Medical Center, 1200 East Broad Street, Richmond, VA, 23298, USA. |
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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