Role of adrenergic alpha-2-receptors on feeding behavior in layer-type chicks. | |
MedLine Citation:
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PMID: 19233186 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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The present study was designed to investigate the role of brain adrenergic alpha-2-receptors on feeding regulation of layer-type chicks. Intracerebroventricular injection of the adrenergic alpha-2-receptor agonist, clonidine, stimulated food intake. This effect was blocked by co-injection of the alpha-2-receptor antagonist, yohimbine, demonstrating that the alpha-2-receptor is related to stimulation of feeding in layer-type chicks. Stimulation of food intake caused by neuropeptide Y and beta-endorphin was attenuated by co-injection with yohimbine. However, yohimbine did not block prolactin-releasing peptide stimulation of food intake. It is therefore likely that brain adrenergic alpha-2-receptors mediate the orexigenic effects of neuropeptide Y and beta-endorphin in layer-type chicks. |
Authors:
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Tetsuya Tachibana; Kunio Sugahara; Hiroshi Ueda; Mark A Cline |
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Publication Detail:
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Type: Journal Article; Research Support, Non-U.S. Gov't Date: 2009-02-20 |
Journal Detail:
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Title: General and comparative endocrinology Volume: 161 ISSN: 1095-6840 ISO Abbreviation: Gen. Comp. Endocrinol. Publication Date: 2009 May |
Date Detail:
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Created Date: 2009-04-07 Completed Date: 2009-08-25 Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 0370735 Medline TA: Gen Comp Endocrinol Country: United States |
Other Details:
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Languages: eng Pagination: 407-11 Citation Subset: IM |
Affiliation:
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Laboratory of Animal Production, Department of Agrobiological Science, Faculty of Agriculture, Ehime University, Tarumi 3-5-7, Matsuyama 790-8566, Japan. tetsu@agr.ehime-u.ac.jp |
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MeSH Terms | |
Descriptor/Qualifier:
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Adrenergic alpha-Agonists
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pharmacology Adrenergic alpha-Antagonists / pharmacology Animals Chickens / physiology* Clonidine / pharmacology Eating / drug effects Feeding Behavior / drug effects, physiology* Male Neuropeptide Y / pharmacology Neurotransmitter Agents / pharmacology Receptors, Adrenergic, alpha-2 / agonists, antagonists & inhibitors, physiology* Yohimbine / pharmacology beta-Endorphin / pharmacology |
Chemical | |
Reg. No./Substance:
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0/Adrenergic alpha-Agonists; 0/Adrenergic alpha-Antagonists; 0/Neuropeptide Y; 0/Neurotransmitter Agents; 0/Receptors, Adrenergic, alpha-2; 146-48-5/Yohimbine; 4205-90-7/Clonidine; 60617-12-1/beta-Endorphin |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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