Document Detail


Role of adrenergic alpha-2-receptors on feeding behavior in layer-type chicks.
MedLine Citation:
PMID:  19233186     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
The present study was designed to investigate the role of brain adrenergic alpha-2-receptors on feeding regulation of layer-type chicks. Intracerebroventricular injection of the adrenergic alpha-2-receptor agonist, clonidine, stimulated food intake. This effect was blocked by co-injection of the alpha-2-receptor antagonist, yohimbine, demonstrating that the alpha-2-receptor is related to stimulation of feeding in layer-type chicks. Stimulation of food intake caused by neuropeptide Y and beta-endorphin was attenuated by co-injection with yohimbine. However, yohimbine did not block prolactin-releasing peptide stimulation of food intake. It is therefore likely that brain adrenergic alpha-2-receptors mediate the orexigenic effects of neuropeptide Y and beta-endorphin in layer-type chicks.
Authors:
Tetsuya Tachibana; Kunio Sugahara; Hiroshi Ueda; Mark A Cline
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Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't     Date:  2009-02-20
Journal Detail:
Title:  General and comparative endocrinology     Volume:  161     ISSN:  1095-6840     ISO Abbreviation:  Gen. Comp. Endocrinol.     Publication Date:  2009 May 
Date Detail:
Created Date:  2009-04-07     Completed Date:  2009-08-25     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  0370735     Medline TA:  Gen Comp Endocrinol     Country:  United States    
Other Details:
Languages:  eng     Pagination:  407-11     Citation Subset:  IM    
Affiliation:
Laboratory of Animal Production, Department of Agrobiological Science, Faculty of Agriculture, Ehime University, Tarumi 3-5-7, Matsuyama 790-8566, Japan. tetsu@agr.ehime-u.ac.jp
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MeSH Terms
Descriptor/Qualifier:
Adrenergic alpha-Agonists / pharmacology
Adrenergic alpha-Antagonists / pharmacology
Animals
Chickens / physiology*
Clonidine / pharmacology
Eating / drug effects
Feeding Behavior / drug effects,  physiology*
Male
Neuropeptide Y / pharmacology
Neurotransmitter Agents / pharmacology
Receptors, Adrenergic, alpha-2 / agonists,  antagonists & inhibitors,  physiology*
Yohimbine / pharmacology
beta-Endorphin / pharmacology
Chemical
Reg. No./Substance:
0/Adrenergic alpha-Agonists; 0/Adrenergic alpha-Antagonists; 0/Neuropeptide Y; 0/Neurotransmitter Agents; 0/Receptors, Adrenergic, alpha-2; 146-48-5/Yohimbine; 4205-90-7/Clonidine; 60617-12-1/beta-Endorphin

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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