| Role of adipokines in complications related to obesity: a review. | |
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MedLine Citation:
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PMID: 19875356 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Worldwide, the prevalence of overweight and obesity and associated complications is increasing. Cardiovascular complications are the most important factor determining survival and influencing clinical management. However, obesity is also associated with an increased risk of metabolic syndrome, type 2 diabetes, cancer and other diseases. The development of complications depends on the amount of body fat and its endocrine function. The hormones (leptin, adiponectin, resistin) and cytokines (TNF alpha, IL-6, PAI-1) produced by the adipose tissue are the link between obesity and obesity-related complications. The present article discusses the structure, function and clinical significance of adipokines. |
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Authors:
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M Gnaci?ska; S Ma?gorzewicz; M Stojek; W ?ysiak-Szyd?owska; K Sworczak |
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Publication Detail:
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Type: Journal Article; Review |
Journal Detail:
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Title: Advances in medical sciences Volume: 54 ISSN: 1898-4002 ISO Abbreviation: Adv Med Sci Publication Date: 2009 |
Date Detail:
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Created Date: 2010-01-11 Completed Date: 2010-03-04 Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 101276222 Medline TA: Adv Med Sci Country: Poland |
Other Details:
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Languages: eng Pagination: 150-7 Citation Subset: IM |
Affiliation:
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Department of Endocrinology and Internal Medicine, Medical University of Gdansk, Poland. |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Adipocytes, White
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physiology Adipokines / chemistry, physiology* Adiponectin / physiology Humans Insulin Resistance / physiology Leptin / physiology Obesity / complications*, physiopathology Resistin / physiology Structure-Activity Relationship |
| Chemical | |
Reg. No./Substance:
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0/Adipokines; 0/Adiponectin; 0/Leptin; 0/Resistin |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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