| Role of vitamin D in blood pressure homeostasis. | |
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MedLine Citation:
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PMID: 20216204 Owner: NLM Status: In-Process |
Abstract/OtherAbstract:
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Hypovitaminosis D is suspected to be linked to several types of cancer, metabolic syndrome, cardiovascular disease, and all-cause mortality. This review explores the relationship of vitamin D to blood pressure and hypertension, a major cardiovascular disease risk factor. The literature up to June 2009 was searched without language or time restrictions from MEDLINE and PubMed, and it was supplemented with references from included studies. Ten observational studies and nine randomized control trials concerned with the association between vitamin D and blood pressure were identified and analyzed. Of these, eight observational studies and three randomized control trials supported an inverse association between vitamin D and blood pressure. Current observational studies strongly support an inverse association between vitamin D and blood pressure, but this association has yet to be convincingly supported with randomized control trials. More research is needed to determine the amount of vitamin D supplementation or ultraviolet B irradiation needed to maintain optimal serum 25-hydroxyvitamin D levels and to lower high blood pressure and to determine who can benefit from vitamin D supplementation or ultraviolet B irradiation. |
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Authors:
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Jennifer F Feneis; Rohit R Arora |
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Publication Detail:
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Type: Journal Article; Research Support, Non-U.S. Gov't |
Journal Detail:
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Title: American journal of therapeutics Volume: 17 ISSN: 1536-3686 ISO Abbreviation: Am J Ther Publication Date: 2010 Nov-Dec |
Date Detail:
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Created Date: 2010-11-09 Completed Date: - Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 9441347 Medline TA: Am J Ther Country: United States |
Other Details:
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Languages: eng Pagination: e221-9 Citation Subset: IM |
Affiliation:
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Chicago Medical School, Chicago, IL, USA. jennifer.feneis@myrfums.org |
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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