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The Role of Smoking and Gingival Crevicular Fluid Markers on Coronally Advanced Flap Outcomes.
MedLine Citation:
PMID:  23725027     Owner:  NLM     Status:  Publisher    
Abstract/OtherAbstract:
Objectives: This study was conducted to evaluate possible effects of smoking on; 1) biochemical content in gingival crevicular fluid (GCF) samples from sites of gingival recession and saliva, 2) clinical outcomes of coronally advanced flap for root coverage. Methods: Eighteen defects in 15 patients were included in each of the smoker and non-smoker groups. Baseline cotinine, basic fibroblast growth factor, vascular endothelial growth factor, platelet-derived growth factor, interleukin-8, interleukin-10, interleukin-12, tumor necrosis factor-alpha, matrix metalloproteinase-8, -9, plasminogen activator inhibitor-1 levels were determined in GCF, saliva samples. Coronally advanced flap with microsurgery technique was applied. Plaque index, papilla bleeding index, recession depth and width, root surface area was evaluated at baseline, postoperative month-1, -3, and -6. Probing depth, clinical attachment level (CAL), keratinized tissue width was recorded at baseline, month-6. Percentage of root coverage, complete root coverage were calculated at postoperative month-1,-3,-6. Results: All biochemical parameters were similar in the two groups apart from the definite difference in salivary cotinine concentrations (P = 0.000). Recession depth, width, CAL, root surface area decreased, keratinized tissue width increased compared to the baseline values with no significant difference between the study groups. CAL gain, percentage of root coverage and complete root coverage rates were similar in the study groups. Conclusion: Similar baseline biochemical data and comparably high success rates of root coverage with coronally advanced flap in systemically and periodontally healthy smoker vs non-smoker individuals suggest lack of adverse effects of smoking on clinical outcomes.
Authors:
Başak Kaval; Diane E Renaud; David A Scott; Nurcan Buduneli
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Publication Detail:
Type:  JOURNAL ARTICLE     Date:  2013-5-31
Journal Detail:
Title:  Journal of periodontology     Volume:  -     ISSN:  1943-3670     ISO Abbreviation:  J. Periodontol.     Publication Date:  2013 May 
Date Detail:
Created Date:  2013-6-3     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  8000345     Medline TA:  J Periodontol     Country:  -    
Other Details:
Languages:  ENG     Pagination:  -     Citation Subset:  -    
Affiliation:
Department of Periodontology, School of Dentistry, Ege University, İzmir, Turkey.
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