Document Detail


The role of second-trimester serum screening in the post-first-trimester screening era.
MedLine Citation:
PMID:  20638580     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Considerable advances have been made in identifying women whose pregnancies are at the greatest risk for fetal Down syndrome and other aneuploidies. Maternal serum tests and ultrasonography in either the first or second trimester provide effective prenatal screening. However, the most efficacious protocols are based on the combination of first- and second-trimester tests. In this article the advantages and best strategies in providing these sequential screening protocols are discussed.
Authors:
Alireza A Shamshirsaz; Peter Benn; James F X Egan
Publication Detail:
Type:  Journal Article; Review    
Journal Detail:
Title:  Clinics in laboratory medicine     Volume:  30     ISSN:  1557-9832     ISO Abbreviation:  Clin. Lab. Med.     Publication Date:  2010 Sep 
Date Detail:
Created Date:  2010-07-19     Completed Date:  2010-11-08     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  8100174     Medline TA:  Clin Lab Med     Country:  United States    
Other Details:
Languages:  eng     Pagination:  667-76     Citation Subset:  IM    
Copyright Information:
Copyright 2010 Elsevier Inc. All rights reserved.
Affiliation:
Department of Obstetrics and Gynecology, Division of Maternal-Fetal Medicine, University of Connecticut Health Center, 263 Farmington Avenue, Farmington, CT 06030-2947, USA.
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MeSH Terms
Descriptor/Qualifier:
Biological Markers / blood*
Down Syndrome / blood,  diagnosis
Female
Fetal Diseases / blood*,  diagnosis
Humans
Mass Screening / methods
Pregnancy
Pregnancy Trimester, Second*
Prenatal Diagnosis / methods*
Chemical
Reg. No./Substance:
0/Biological Markers

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