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Role of Ribose Deficit in Rat Testicular Metabolism under Conditions of Overtraining.
MedLine Citation:
PMID:  22235407     Owner:  NLM     Status:  In-Data-Review    
Abstract/OtherAbstract:
Acute disorders of purine metabolism develop in rat testes under conditions of overtraining. These disorders are characterized by enhanced catabolism and reduced reutilization of purine mononucleotides and activation of lipid peroxidation of membrane structures against the background of reduced activities of the pentose cycle and antioxidant system. Administration of D-ribose to rats subjected to overtraining improves purine reutilization, stimulates the pentose cycle work, inhibits lipid peroxidation in membrane structures of the testes, and saves the testicular incretory function.
Authors:
V D Conway; B A Race; E A Chigrinskiy
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Bulletin of experimental biology and medicine     Volume:  150     ISSN:  1573-8221     ISO Abbreviation:  Bull. Exp. Biol. Med.     Publication Date:  2011 Mar 
Date Detail:
Created Date:  2012-01-11     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  0372557     Medline TA:  Bull Exp Biol Med     Country:  United States    
Other Details:
Languages:  eng; rus     Pagination:  649-51     Citation Subset:  IM    
Affiliation:
Department of Chemistry, Omsk State Agrarian University; Central Research Laboratory, Omsk State Medical Academy, Russia. chigrinski@list.ru.
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