Document Detail

Role of Purkinje conducting system in triggering of idiopathic ventricular fibrillation.
MedLine Citation:
PMID:  11879868     Owner:  NLM     Status:  MEDLINE    
Ventricular fibrillation is the main mechanism of sudden cardiac death, but the source of its spontaneous initiation has not been mapped. 16 patients were investigated by electrography and radiofrequency ablation after resuscitation from recurrent idiopathic ventricular fibrillation. Triggers of ventricular fibrillation originated from various locations within the Purkinje system in 12 patients and from the ordinary myocardial muscle in four. The accuracy of mapping was confirmed by acute elimination of triggers by radiofrequency delivery, and there was no recurrence of ventricular fibrillation in 14 patients. Long-term follow-up is necessary to establish that ablation is curative and avoids use of a defibrillator.
Michel Haïssaguerre; Dipen C Shah; Pierre Jaïs; Morio Shoda; Josef Kautzner; Thomas Arentz; Dietrich Kalushe; Alan Kadish; Mike Griffith; Fiorenzo Gaïta; Teiichi Yamane; Stephane Garrigue; Meleze Hocini; Jacques Clémenty
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Lancet     Volume:  359     ISSN:  0140-6736     ISO Abbreviation:  Lancet     Publication Date:  2002 Feb 
Date Detail:
Created Date:  2002-03-06     Completed Date:  2002-03-22     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  2985213R     Medline TA:  Lancet     Country:  England    
Other Details:
Languages:  eng     Pagination:  677-8     Citation Subset:  AIM; IM    
Hôpital Cardiologique du Haut-Lévêque, Bordeaux-Pessac, France.
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MeSH Terms
Catheter Ablation
Middle Aged
Purkinje Fibers / physiology*
Ventricular Fibrillation / physiopathology*,  therapy

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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