Document Detail

Role of Platelets in Neurodegenerative Diseases: A Universal Pathophysiology.
MedLine Citation:
PMID:  23301959     Owner:  NLM     Status:  Publisher    
Abstract Platelets play an important role in a variety of disorders viz; cardiovascular, psychosomatic, psychiatric, thrombosis, HIV/AIDS in addition to various neurodegenerative diseases (NDD). Recent evidence indicates that platelet react to diverse stressors thereby offering an interesting vantage point for understanding their potential role in contemporary medical research. This review addresses the possible role of platelets as a systemic probe in various NDD's such as Amyotrophic Lateral Sclerosis (ALS), Parkinson's Disease (PD), Huntington's Disease (HD), Alzheimer's Disease (AD), Multiple Sclerosis (MS) etc. The current review based on published literature, describes a probable link between platelets and pathophysiology of various NDD's. It also discusses how platelets epitomize ultra structural, morphological, biochemical and molecular changes, highlighting their emerging role as systemic tools in different NDD's.
Professor Madhuri Behari; Dr Mohita Shrivastava
Related Documents :
22652599 - Fractalkine activates a signal transduction pathway similar to p2y12 and is associated ...
22910089 - Coagulation management in patients undergoing mechanical circulatory support.
23301959 - Role of platelets in neurodegenerative diseases: a universal pathophysiology.
22911769 - Platelet-derived toll-like receptor 4 (tlr-4) is sufficient to promote microvascular th...
6116859 - Migraine: a platelet disorder.
2962739 - Platelet activation in muscle contraction headache and migraine.
22677379 - Identification of different proaggregatory abilities of activated platelet subpopulations.
9873379 - Synthesis and pharmacological activities of 13-dehydro derivatives of primary prostagla...
14644569 - Effects of ultraviolet b on epidermal morphology, shedding, lipid peroxide, and antioxi...
Publication Detail:
Type:  JOURNAL ARTICLE     Date:  2013-1-10
Journal Detail:
Title:  The International journal of neuroscience     Volume:  -     ISSN:  1563-5279     ISO Abbreviation:  Int. J. Neurosci.     Publication Date:  2013 Jan 
Date Detail:
Created Date:  2013-1-10     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  0270707     Medline TA:  Int J Neurosci     Country:  -    
Other Details:
Languages:  ENG     Pagination:  -     Citation Subset:  -    
All India Institute of Medical Sciences, Neurology , Ansari Nagar, New Delhi , 110029 India.
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

Previous Document:  Imaging actinic keratosis by high-definition optical coherence tomography. Histomorphologic correlat...
Next Document:  Avoidance of noninfectious sternal dehiscence: figure-of-8 wiring is superior to straight wire closu...