| The Role of Phenotyping in Chronic Prostatitis/Chronic Pelvic Pain Syndrome. | |
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MedLine Citation:
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PMID: 21533747 Owner: NLM Status: Publisher |
Abstract/OtherAbstract:
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Chronic prostatitis/chronic pelvic pain syndrome (CP/CPPS) is a chronic pain syndrome identified by the presence of noninfectious pelvic or perineal pain lasting longer than 3 months. Current diagnoses and treatments for the syndrome solely depend on and target symptoms, respectively. Thus far, the mechanistic disturbances responsible for the pathogenesis of CP/CPPS have remained largely elusive and treatments, and therefore, continue to be ineffective. To move toward successful management and treatment of CP/CPPS, it is necessary to elicit the underlying biological mechanisms responsible for the syndrome. Therefore, a phenotyping system that is able to bridge the gap between current symptom-based diagnosis and future mechanistic approaches to diagnosis and treatment is needed. In this article, we examine current CP/CPPS phenotyping systems, analyze their utility, and make suggestions for changes in clinical approaches to the syndrome that would both promulgate a mechanistic understanding and advance treatment approaches. |
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Authors:
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Brandon A Mahal; Jeffrey M Cohen; Stephen A Allsop; John B Moore; Salman F Bhai; Gino Inverso; Jordan D Dimitrakoff |
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Publication Detail:
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Type: JOURNAL ARTICLE Date: 2011-4-28 |
Journal Detail:
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Title: Current urology reports Volume: - ISSN: 1534-6285 ISO Abbreviation: - Publication Date: 2011 Apr |
Date Detail:
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Created Date: 2011-5-2 Completed Date: - Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 100900943 Medline TA: Curr Urol Rep Country: - |
Other Details:
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Languages: ENG Pagination: - Citation Subset: - |
Affiliation:
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Harvard Medical School, 25 Shattuck Street, Boston, MA, 02115, USA. |
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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