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The Role of Multiple Drug Therapy for Controlling Hypertension in African Americans.
MedLine Citation:
PMID:  11416633     Owner:  NLM     Status:  Publisher    
Abstract/OtherAbstract:
Hypertension among black Americans explains much of the black health disadvantage. Compared with white Americans, blacks develop hypertension at a younger age and have higher rates of stage 3 hypertension (i.e., blood pressure is greater than 180/110 mm Hg). Black Americans tend to wait longer for treatment after diagnosis, causing a longer duration of elevated blood pressure and greater target organ damage. To arrive at the recommended target blood pressure of less than 130/85 mm Hg (in patients with diabetes or renal failure) or 125/75 mm Hg (in patients with proteinuria greater than 1 g/24 hours), all antihypertensive drug classes can be considered. Tight blood pressure control in black Americans frequently requires the use of more than just one agent (monotherapy). Low dose combination therapy, such as a calcium channel blocker and an ACE inhibitor, can solve many of the clinical issues that must be considered when treating hypertension in this patient group. (c)2000 by Le Jacq Communications, Inc.
Authors:
Matthew R. Weir
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Publication Detail:
Type:  JOURNAL ARTICLE    
Journal Detail:
Title:  Journal of clinical hypertension (Greenwich, Conn.)     Volume:  2     ISSN:  1751-7176     ISO Abbreviation:  J Clin Hypertens (Greenwich)     Publication Date:  2000 Mar 
Date Detail:
Created Date:  2001-Jun-20     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  100888554     Medline TA:  J Clin Hypertens (Greenwich)     Country:  -    
Other Details:
Languages:  ENG     Pagination:  99-108     Citation Subset:  -    
Affiliation:
Division of Nephrology and Clinical Research Unit, University of Maryland School of Medicine, Baltimore, MD.
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