| Role of Momordica charantia in maintaining the normal levels of lipids and glucose in diabetic rats fed a high-fat and low-carbohydrate diet. | |
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MedLine Citation:
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PMID: 16196458 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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This study aims to assess whether or not a methanol extract of Momordica charantia is able to normalise lipid and glucose levels in diabetic rats fed a high-fat and a low-carbohydrate diet. Different doses of the extract are administered orally for 45 days. The rats are bled at the beginning of the experiment and at 15-day intervals. Blood glucose, triglyceride, low-density lipoprotein (LDL), high-density lipoprotein (HDL) and cholesterol are estimated. Results showed that M. charantia extract normalised blood glucose level, reduced triglyceride and LDL levels and increased HDL level. The animals reverted to a diabetic state once the M. charantia extract was discontinued. |
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Authors:
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P Chaturvedi |
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Publication Detail:
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Type: Comparative Study; Journal Article; Research Support, Non-U.S. Gov't |
Journal Detail:
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Title: British journal of biomedical science Volume: 62 ISSN: 0967-4845 ISO Abbreviation: Br. J. Biomed. Sci. Publication Date: 2005 |
Date Detail:
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Created Date: 2005-10-03 Completed Date: 2006-02-09 Revised Date: 2006-11-15 |
Medline Journal Info:
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Nlm Unique ID: 9309208 Medline TA: Br J Biomed Sci Country: England |
Other Details:
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Languages: eng Pagination: 124-6 Citation Subset: IM |
Affiliation:
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Department of Biological Sciences, University of Botswana, P/Bag 0074 Gaborone, Botswana. chaturve@mopipi.ub.bw |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Animals Blood Glucose / metabolism* Cholesterol / blood Diabetes Mellitus, Experimental / blood* Dietary Carbohydrates / administration & dosage* Lipids / blood* Lipoproteins, HDL / blood Lipoproteins, LDL / blood Male Momordica charantia* Plant Extracts / administration & dosage* Rats Rats, Inbred Strains Triglycerides / blood |
| Chemical | |
Reg. No./Substance:
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0/Blood Glucose; 0/Dietary Carbohydrates; 0/Lipids; 0/Lipoproteins, HDL; 0/Lipoproteins, LDL; 0/Plant Extracts; 0/Triglycerides; 57-88-5/Cholesterol |
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