| Role of Limited Whole-Body PET/CT in Pediatric Lymphoma. | |
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MedLine Citation:
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PMID: 21512070 Owner: NLM Status: In-Data-Review |
Abstract/OtherAbstract:
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OBJECTIVE: Performing true whole-body FDG PET/CT is standard practice in pediatric lymphoma staging and follow-up. In adults, imaging is typically limited whole-body PET/CT, which has advantages over true whole-body PET/CT, primarily decreased scanning time and decreased radiation. We hypothesize that in pediatric lymphoma, limited whole-body PET/CT is sufficient for routine follow-up when disease on the true whole-body staging study is confined to the limited whole-body field of view (FOV). MATERIALS AND METHODS: True whole-body PET/CT studies performed for staging and follow-up of pediatric lymphoma patients between November 2004 and July 2009 at two tertiary pediatric referral hospitals were retrospectively reviewed. Abnormalities on the limited whole-body and additional true whole-body FOV were documented. RESULTS: One hundred seventy patients met the inclusion criteria (752 examinations). At staging, disease involved the limited whole-body FOV without involving the additional true whole-body FOV in 150. Of the 150, 145 had routine follow-up (508 examinations). In these patients, no new (18)F-FDG-avid disease was identified outside of the limited whole-body FOV on routine follow-up (positive predictive value, 0%, 95% CI, 0-0.02). CONCLUSION: The limited whole-body PET/CT for routine follow-up when disease is confined to the limited whole-body FOV at staging is appropriate. Given its definite advantages over true whole-body PET/CT, it is preferred. |
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Authors:
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Marla B K Sammer; Barry L Shulkin; Adam Alessio; Marguerite T Parisi |
Publication Detail:
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Type: Journal Article |
Journal Detail:
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Title: AJR. American journal of roentgenology Volume: 196 ISSN: 1546-3141 ISO Abbreviation: AJR Am J Roentgenol Publication Date: 2011 May |
Date Detail:
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Created Date: 2011-04-22 Completed Date: - Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 7708173 Medline TA: AJR Am J Roentgenol Country: United States |
Other Details:
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Languages: eng Pagination: 1047-55 Citation Subset: AIM; IM |
Affiliation:
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Department of Radiology, University of Washington and Seattle Children's Hospital, 4800 Sand Point Way, R-5417, Seattle, WA 98105. |
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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