Document Detail


The role of imaging in the diagnosis of central nervous system vasculitis.
MedLine Citation:
PMID:  20425011     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Cerebral vasculitis is diagnosed with difficulty. Its presentation with heterogeneous symptoms and signs often delays diagnosis. In this context, imaging plays an important role in advancing the diagnosis. Digital subtraction cerebral angiography, MRI, and MRA, the most useful examinations for vasculitis, provide supportive, but not pathognomonic, evidence of cerebral vasculitis. On MRI, multiple infarcts in different vascular territories and of different ages are suggestive of vasculitis. On digital subtraction cerebral angiography, areas of stenosis, dilatation, and occlusion are suggestive of vasculitis. Small vessel vasculitis is currently best demonstrated by changes seen in brain parenchyma on MRI, but high field strength (7 T) magnetic resonance angiography offers the possibility of directly evaluating small vessel vasculitis. Ultrasound and high-resolution contrast MRI are excellent modalities for evaluating the superficial extracranial circulation.
Authors:
Lavier J Gomes
Publication Detail:
Type:  Journal Article; Review    
Journal Detail:
Title:  Current allergy and asthma reports     Volume:  10     ISSN:  1534-6315     ISO Abbreviation:  Curr Allergy Asthma Rep     Publication Date:  2010 May 
Date Detail:
Created Date:  2010-05-05     Completed Date:  2010-08-16     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  101096440     Medline TA:  Curr Allergy Asthma Rep     Country:  United States    
Other Details:
Languages:  eng     Pagination:  163-70     Citation Subset:  IM    
Affiliation:
Department of Radiology, Centre for Biomedical Imaging Research and Development, Sydney Medical School, University of Sydney, Westmead Hospital, Darcy Road, Westmead, NSW, 2145, Sydney, Australia. lavier.gomes@sydney.edu.au
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MeSH Terms
Descriptor/Qualifier:
Age Factors
Angiography, Digital Subtraction
Brain / pathology,  radiography
Cerebral Angiography
Cerebral Infarction / radiography,  ultrasonography
Constriction, Pathologic / radiography,  ultrasonography
Diagnosis, Differential
Humans
Magnetic Resonance Angiography
Ultrasonography, Doppler, Color
Vasculitis, Central Nervous System / diagnosis*,  pathology

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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