Document Detail

Role of EUS/EUS-guided FNA in the management of proximal biliary strictures.
MedLine Citation:
PMID:  22234054     Owner:  NLM     Status:  MEDLINE    
BACKGROUND/AIMS: Optimal management of proximal biliary strictures depends on staging and adequate tissue diagnosis of suspected malignant lesions. Sensitivity of ERCP brush cytology is poor. EUS/EUS-FNA of these lesions is challenging with limited data on its diagnostic accuracy. We report our experience of EUS/ EUS guided FNA of proximal biliary strictures in a tertiary referral centre.
METHODOLOGY: All patients who underwent EUS guided FNA of hilar lesions between October 2003 to July 2007 were identified. The final diagnosis was determined by surgical pathology, results of EUS-FNA or follow-up.
RESULTS: 32 patients underwent 36 procedures for hilar lesions during the study period. EUS detected a mass in 9/14 patients who did not have a mass seen on imaging. The mean followup period was 39.43 months. The cytological specimen was adequate in 26 patients. The final diagnosis was adenocarcinoma (24) and benign (8). The overall accuracy, sensitivity, specificity, positive predictive value and negative predictive value of EUS-FNA were 68%, 52 %, 100%, 100% and 54%, respectively. If only adequate aspirates were included in the analysis, the values were 74%, 60%, 100%, 100% and 55% respectively.
CONCLUSIONS: EUS guided FNA is a useful modality in the diagnosis and management of hilar lesions.
Manu K Nayar; Nayar K Manu; Derek M Manas; Manas M Derek; Viney Wadehra; Wadehra Viney; Kofi E Oppong; Oppong E Kofi
Related Documents :
22211034 - Thyroglossal duct cyst-more than just an embryological remnant.
24194164 - Differentiation of mucinous cystic neoplasm and cystic changes associated with pancreat...
21829424 - Sexual history: its importance in averting detrimental misdiagnosis and delayed diagnosis.
23408024 - Transsphenoidal meningocele: an anatomical study using human fetuses including report o...
3920544 - Osteosclerotic myeloma complicated by diffuse arteritis, vascular calcification and ext...
19963354 - Colorimetric analysis of unstained lesions surrounding oral squamous cell carcinomas an...
Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Hepato-gastroenterology     Volume:  58     ISSN:  0172-6390     ISO Abbreviation:  Hepatogastroenterology     Publication Date:    2011 Nov-Dec
Date Detail:
Created Date:  2012-01-11     Completed Date:  2012-03-27     Revised Date:  2013-03-18    
Medline Journal Info:
Nlm Unique ID:  8007849     Medline TA:  Hepatogastroenterology     Country:  Greece    
Other Details:
Languages:  eng     Pagination:  1862-5     Citation Subset:  IM    
Department of Gastroenterology, Freeman hospital, Newcastle upon Tyne, UK.
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms
Aged, 80 and over
Bile Duct Neoplasms / diagnosis*,  pathology,  ultrasonography
Bile Ducts, Intrahepatic*
Biopsy, Fine-Needle / methods*
Cholangiocarcinoma / diagnosis*,  pathology,  ultrasonography
Cholestasis / diagnosis*,  pathology,  ultrasonography
Endosonography / methods*
Middle Aged
Retrospective Studies
Erratum In:
Hepatogastroenterology. 2012 Mar-Apr;59(114):664
Note: Manu, Nayar K [corrected to Nayar, Manu K]; Derek, Manas M [corrected to Manas, Derek M]; Viney, Wadehra [corrected to Wadehra, Viney]; Kofi, Oppong E [corrected to Oppong, Kofi E]

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

Previous Document:  Novel treatments for vasospasm after subarachnoid hemorrhage.
Next Document:  Phase I trial of neoadjuvant chemoradiation with gemcitabine and surgical resection for cholangiocar...