| Role of FDG PET/CT in Staging of Recurrent Ovarian Cancer. | |
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MedLine Citation:
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PMID: 21415197 Owner: NLM Status: In-Data-Review |
Abstract/OtherAbstract:
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Ovarian cancer is the fifth leading cause of cancer death among women in the United States and has a high likelihood of recurrence despite aggressive treatment strategies. Detection and exact localization of recurrent lesions are critical for guiding management and determining the proper therapeutic approach, which may prolong survival. Because of its high sensitivity and specificity compared with those of conventional techniques such as computed tomography (CT) and magnetic resonance (MR) imaging, fluorine 18 fluorodeoxyglucose positron emission tomography (PET) combined with CT is useful for detection of recurrent or residual ovarian cancer and for monitoring response to therapy. However, PET/CT may yield false-negative results in patients with small, necrotic, mucinous, cystic, or low-grade tumors. In addition, in the posttherapy setting, inflammatory and infectious processes may lead to false-positive PET/CT results. Despite these drawbacks, PET/CT is superior to CT and MR imaging for depiction of recurrent disease. © RSNA, 2011. |
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Authors:
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Hongju Son; Shahid M Khan; Jamal Rahaman; Katherine L Cameron; Monica Prasad-Hayes; Linus Chuang; Josef Machac; Sherif Heiba; Lale Kostakoglu |
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Publication Detail:
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Type: Journal Article |
Journal Detail:
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Title: Radiographics : a review publication of the Radiological Society of North America, Inc Volume: 31 ISSN: 1527-1323 ISO Abbreviation: Radiographics Publication Date: 2011 Mar-Apr |
Date Detail:
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Created Date: 2011-03-18 Completed Date: - Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 8302501 Medline TA: Radiographics Country: United States |
Other Details:
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Languages: eng Pagination: 569-83 Citation Subset: IM |
Affiliation:
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Division of Nuclear Medicine, Department of Radiology and the Division of Gynecological Oncology, Department of Obstetrics, Gynecology, and Reproductive Medicine, Mount Sinai School of Medicine, One Gustave L. Levy Place, Box 1141, New York, NY 10029. |
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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