| Role of CCR2 and IL-8 in acute lung injury: a new mechanism and therapeutic target. | |
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MedLine Citation:
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PMID: 21348591 Owner: NLM Status: In-Data-Review |
Abstract/OtherAbstract:
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Acute lung injury (ALI) and acute respiratory distress syndrome (ARDS) are severe inflammatory lung diseases associated with very high mortality, and are the most common and earliest organ dysfunctions in the development of multiple organ dysfunction syndrome. The NIH estimates that more than 4.5 million people suffer from ALI/ARDS per year. Although the American-European Consensus Conference definition has been widely used for approximately 40 years, it still has some limitations that may impact on the conduct of clinical research and management of patients with ALI/ARDS. This article will focus on the role of CC chemokine receptor 2 and IL-8 in the pathogenesis and resolution in ALI/ARDS. |
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Authors:
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Yao Shen; Diane Wang; Xiangdong Wang |
Publication Detail:
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Type: Journal Article |
Journal Detail:
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Title: Expert review of respiratory medicine Volume: 5 ISSN: 1747-6356 ISO Abbreviation: Expert Rev Respir Med Publication Date: 2011 Feb |
Date Detail:
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Created Date: 2011-02-25 Completed Date: - Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 101278196 Medline TA: Expert Rev Respir Med Country: England |
Other Details:
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Languages: eng Pagination: 107-14 Citation Subset: IM |
Affiliation:
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Department of Pulmonary Medicine, Center for Biomedical Research, Zhongshan Hospital, Fudan University, PR China. |
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Descriptor/Qualifier:
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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