| Rod and cone contrast gains derived from reaction time distribution modeling. | |
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MedLine Citation:
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PMID: 20462312 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Contrast gain reflects the rapidity of response amplitude increase with increase in stimulus contrast. In physiology, contrast gain can be measured directly as the initial slope of cell contrast response function. In psychophysics, contrast gain estimation is not straightforward. Further, rod and cone contrast gains have not been measured psychophysically at mesopic light levels where both rods and cones are active, due to the difficulty in producing stimuli that excite rods and cones separately at the same adaptation level. Here, we estimated rod and contrast gains by fitting reaction time distributions measured at a light level in which rods alone (scotopic), rods and cones (mesopic), or cones alone (photopic) mediate vision. The reaction time distributions were modeled by two different strategies, a simplified diffusion model that assumes a stochastic accumulation process and a model we developed that begins with sensory input based on early visual processing impulse response functions and assumes the reaction time variability originates in the response criterion. Estimates of contrast gain from both models were comparable and consistent with primate physiology measurements. |
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Authors:
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Dingcai Cao; Joel Pokorny |
Publication Detail:
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Type: Journal Article; Research Support, N.I.H., Extramural Date: 2010-02-12 |
Journal Detail:
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Title: Journal of vision Volume: 10 ISSN: 1534-7362 ISO Abbreviation: J Vis Publication Date: 2010 |
Date Detail:
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Created Date: 2010-05-13 Completed Date: 2010-08-13 Revised Date: 2011-10-17 |
Medline Journal Info:
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Nlm Unique ID: 101147197 Medline TA: J Vis Country: United States |
Other Details:
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Languages: eng Pagination: 11.1-15 Citation Subset: IM |
Affiliation:
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Department of Surgery, Section of Ophthalmology and Visual Science, The University of Chicago, Chicago, IL, USA. d-cao@uchicago.edu |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Adaptation, Ocular
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physiology Animals Color Vision / physiology Contrast Sensitivity / physiology* Dark Adaptation / physiology Models, Neurological* Photic Stimulation / methods Primates Psychophysics Reaction Time / physiology Retinal Cone Photoreceptor Cells / physiology* Retinal Rod Photoreceptor Cells / physiology* Sensory Thresholds / physiology |
| Grant Support | |
ID/Acronym/Agency:
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EY00901/EY/NEI NIH HHS |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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